Current understanding and perspectives in anaerobic digestion based on genome-resolved metagenomic approaches

Na Kyung Kim, Sang Hoon Lee, Yonghoon Kim, Hee Deung Park

Research output: Contribution to journalReview articlepeer-review

28 Citations (Scopus)


Anaerobic digestion (AD) is a technique that can be used to treat high concentrations of various organic wastes using a consortium of functionally diverse microorganisms under anaerobic conditions. Methane gas, a beneficial by-product of the AD process, is a renewable energy source that can replace fossil fuels following purification. However, detailed functional roles and metabolic interactions between microbial populations involved in organic waste removal and methanogenesis are yet to be known. Recent metagenomic approaches based on advanced high-throughput sequencing techniques have enabled the exploration of holistic microbial taxonomy and functionality of complex microbial populations involved in the AD process. Gene-centric and genome-centric analyses based on metagenome-assembled genomes are a platform that can be used to study the composition of microbial communities and their roles during AD. This review looks at how these up-to-date metagenomic analyses can be applied to promote our understanding and improved the development of the AD process.

Original languageEnglish
Article number126350
JournalBioresource technology
Publication statusPublished - 2022 Jan

Bibliographical note

Publisher Copyright:
© 2021 Elsevier Ltd


  • Anaerobic digestion
  • Genome-centric analysis
  • Metagenomics
  • Microbial community
  • Next-generation sequencing

ASJC Scopus subject areas

  • Bioengineering
  • Environmental Engineering
  • Renewable Energy, Sustainability and the Environment
  • Waste Management and Disposal


Dive into the research topics of 'Current understanding and perspectives in anaerobic digestion based on genome-resolved metagenomic approaches'. Together they form a unique fingerprint.

Cite this