@article{500842202303421a905e1d845ccf0255,
title = "Cytotoxic 6-alkylsalicylic acids from the endophytic Streptomyces laceyi",
abstract = "Two new 6-alkylsalicylic acids, salaceyins A and B were isolated by bioassay-guided fractionation from the culture of the endophytic Streptomyces laceyi MS53 and their structures were determined on the basis of spectroscopic data. Salaceyins A and B exhibited modest cytotoxicity against a human breast cancer cell line (SKBR3) with IC50 values of 3.0 and 5.5 μg/ml, respectively.",
keywords = "Alkysalicylic acid, Cytotoxic, Streptomyces",
author = "Nahyun Kim and Shin, {Jin Chul} and Woncheol Kim and Hwang, {Bang Yeon} and Kim, {Beom Seok} and Hong, {Young Soo} and Dongho Lee",
note = "Funding Information: Acknowledgements The work was supported by the 21C Frontier Microbial Genomics and Applications Center (MG05-0303-2-0 to Y.-S.H.), Ministry of Science and Technology, Republic of Korea and by the BioGreen21 Program (20050301034453 to B. S. Kim), Rural Development Administration, Republic of Korea. We thank the Korea Basic Science Institute for providing certain instruments used in this study.",
year = "2006",
month = dec,
doi = "10.1038/ja.2006.105",
language = "English",
volume = "59",
pages = "797--800",
journal = "Journal of Antibiotics",
issn = "0021-8820",
publisher = "Japan Antibiotics Research Association",
number = "12",
}
