De-enhancing the dynamic contrast-enhanced breast MRI for robust registration

Yuanjie Zheng, Jingyi Yu, Chandra Kambhamettu, Sarah Englander, Mitchell D. Schnall, Dinggang Shen

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    30 Citations (Scopus)

    Abstract

    Dynamic enhancement causes serious problems for registration of contrast enhanced breast MRI, due to variable uptakes of agent on different tissues or even same tissues in the breast. We present an iterative optimization algorithm to de-enhance the dynamic contrastenhanced breast MRI and then register them for avoiding the effects of enhancement on image registration. In particular, the spatially varying enhancements are modeled by a Markov Random Field, and estimated by a locally smooth function with boundaries using a graph cut algorithm. The de-enhanced images are then registered by conventional Bspline based registration algorithm. These two steps benefit from each other and are repeated until the results converge. Experimental results show that our two-step registration algorithm performs much better than conventional mutual information based registration algorithm. Also, the effects of tumor shrinking in the conventional registration algorithms can be effectively avoided by our registration algorithm.

    Original languageEnglish
    Title of host publicationMedical Image Computing and Computer-Assisted Intervention - 10th International Conference, Proceedings
    PublisherSpringer Verlag
    Pages933-941
    Number of pages9
    Volume4791 LNCS
    EditionPART 1
    ISBN (Print)9783540757566
    DOIs
    Publication statusPublished - 2007
    Event10th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2007 - Brisbane, Australia
    Duration: 2007 Oct 292007 Nov 2

    Publication series

    NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
    NumberPART 1
    Volume4791 LNCS
    ISSN (Print)0302-9743
    ISSN (Electronic)1611-3349

    Other

    Other10th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2007
    Country/TerritoryAustralia
    CityBrisbane
    Period07/10/2907/11/2

    ASJC Scopus subject areas

    • Theoretical Computer Science
    • General Computer Science

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