Decursinol angelate: A cytotoxic and protein kinase C activating agent from the root of Angelica gigas

Kyung Seop Ahn, Woong Seop Sim, In Kuk Lee, Young Bae Seu, Ik Hwan Kim

    Research output: Contribution to journalArticlepeer-review

    67 Citations (Scopus)

    Abstract

    A cytotoxic compound was purified from the root of Angelica gigas Nakai by normal phase HPLC. As a result of the structure analysis by mass, IR, 1H-NMR, and 13C-NMR spectrometry, the compound was identified as decursinol angelate, a structural isomer of decursin, and characterized originally from Sesei grandivittatum. Decursinol angelate showed in vitro cytotoxicity and protein kinase C activating activities like decursin.

    Original languageEnglish
    Pages (from-to)360-361
    Number of pages2
    JournalPlanta Medica
    Volume63
    Issue number4
    DOIs
    Publication statusPublished - 1997

    ASJC Scopus subject areas

    • Analytical Chemistry
    • Molecular Medicine
    • Pharmacology
    • Pharmaceutical Science
    • Drug Discovery
    • Complementary and alternative medicine
    • Organic Chemistry

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