Defining CT Perfusion Thresholds for Infarction in the Golden Hour and with Ultra-Early Reperfusion

Mohamed Najm; Fahad S. Al-Ajlan; Mari E. Boesen; Lisa Hur; Chi Kyung Kim; Enrico Fainardi; Michael D. Hill; Andrew M. Demchuk; Mayank Goyal; Ting Y. Lee; Bijoy K. Menon

doi:10.1017/cjn.2017.287

Defining CT Perfusion Thresholds for Infarction in the Golden Hour and with Ultra-Early Reperfusion

Mohamed Najm, Fahad S. Al-Ajlan, Mari E. Boesen, Lisa Hur, Chi Kyung Kim, Enrico Fainardi, Michael D. Hill, Andrew M. Demchuk, Mayank Goyal, Ting Y. Lee, Bijoy K. Menon

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

In this brief report, computed tomography perfusion (CTP) thresholds predicting follow-up infarction in patients presenting <3 hours from stroke onset and achieving ultra-early reperfusion (<45 minutes from CTP) are reported. CTP thresholds that predict follow-up infarction vary based on time to reperfusion: Tmax >20 to 23 seconds and cerebral blood flow <5 to 7 ml/min ^-1 /(100 g) ^-1 or relative cerebral blood flow <0.14 to 0.20 optimally predicted the final infarct. These thresholds are stricter than published thresholds.

Original language	English
Pages (from-to)	339-342
Number of pages	4
Journal	Canadian Journal of Neurological Sciences
Volume	45
Issue number	3
DOIs	https://doi.org/10.1017/cjn.2017.287
Publication status	Published - 2018 May 1

Bibliographical note

Publisher Copyright:
© 2018 The Canadian Journal of Neurological Sciences Inc.

Keywords

CT perfusion
early reperfusion
endovascular therapy

ASJC Scopus subject areas

Neurology
Clinical Neurology

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10.1017/cjn.2017.287

Cite this

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title = "Defining CT Perfusion Thresholds for Infarction in the Golden Hour and with Ultra-Early Reperfusion",

abstract = " In this brief report, computed tomography perfusion (CTP) thresholds predicting follow-up infarction in patients presenting <3 hours from stroke onset and achieving ultra-early reperfusion (<45 minutes from CTP) are reported. CTP thresholds that predict follow-up infarction vary based on time to reperfusion: Tmax >20 to 23 seconds and cerebral blood flow <5 to 7 ml/min -1 /(100 g) -1 or relative cerebral blood flow <0.14 to 0.20 optimally predicted the final infarct. These thresholds are stricter than published thresholds. ",

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AU - Kim, Chi Kyung

AU - Fainardi, Enrico

AU - Hill, Michael D.

AU - Demchuk, Andrew M.

AU - Goyal, Mayank

AU - Lee, Ting Y.

AU - Menon, Bijoy K.

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Defining CT Perfusion Thresholds for Infarction in the Golden Hour and with Ultra-Early Reperfusion

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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