Defining CT Perfusion Thresholds for Infarction in the Golden Hour and with Ultra-Early Reperfusion

Mohamed Najm; Fahad S. Al-Ajlan; Mari E. Boesen; Lisa Hur; Chi Kyung Kim; Enrico Fainardi; Michael D. Hill; Andrew M. Demchuk; Mayank Goyal; Ting Y. Lee; Bijoy K. Menon

doi:10.1017/cjn.2017.287

Defining CT Perfusion Thresholds for Infarction in the Golden Hour and with Ultra-Early Reperfusion

Mohamed Najm, Fahad S. Al-Ajlan, Mari E. Boesen, Lisa Hur, Chi Kyung Kim, Enrico Fainardi, Michael D. Hill, Andrew M. Demchuk, Mayank Goyal, Ting Y. Lee, Bijoy K. Menon

* New professors

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

In this brief report, computed tomography perfusion (CTP) thresholds predicting follow-up infarction in patients presenting <3 hours from stroke onset and achieving ultra-early reperfusion (<45 minutes from CTP) are reported. CTP thresholds that predict follow-up infarction vary based on time to reperfusion: Tmax >20 to 23 seconds and cerebral blood flow <5 to 7 ml/min ^-1 /(100 g) ^-1 or relative cerebral blood flow <0.14 to 0.20 optimally predicted the final infarct. These thresholds are stricter than published thresholds.

Original language	English
Pages (from-to)	339-342
Number of pages	4
Journal	Canadian Journal of Neurological Sciences
Volume	45
Issue number	3
DOIs	https://doi.org/10.1017/cjn.2017.287
Publication status	Published - 2018 May 1

Keywords

CT perfusion
early reperfusion
endovascular therapy

ASJC Scopus subject areas

Neurology
Clinical Neurology

Access to Document

10.1017/cjn.2017.287

Cite this

@article{af7534ffdb5942249d54a148eccbc2e3,

title = "Defining CT Perfusion Thresholds for Infarction in the Golden Hour and with Ultra-Early Reperfusion",

abstract = " In this brief report, computed tomography perfusion (CTP) thresholds predicting follow-up infarction in patients presenting <3 hours from stroke onset and achieving ultra-early reperfusion (<45 minutes from CTP) are reported. CTP thresholds that predict follow-up infarction vary based on time to reperfusion: Tmax >20 to 23 seconds and cerebral blood flow <5 to 7 ml/min -1 /(100 g) -1 or relative cerebral blood flow <0.14 to 0.20 optimally predicted the final infarct. These thresholds are stricter than published thresholds. ",

keywords = "CT perfusion, early reperfusion, endovascular therapy",

author = "Mohamed Najm and Al-Ajlan, {Fahad S.} and Boesen, {Mari E.} and Lisa Hur and Kim, {Chi Kyung} and Enrico Fainardi and Hill, {Michael D.} and Demchuk, {Andrew M.} and Mayank Goyal and Lee, {Ting Y.} and Menon, {Bijoy K.}",

note = "Publisher Copyright: {\textcopyright} 2018 The Canadian Journal of Neurological Sciences Inc.",

year = "2018",

month = may,

day = "1",

doi = "10.1017/cjn.2017.287",

language = "English",

volume = "45",

pages = "339--342",

journal = "Canadian Journal of Neurological Sciences",

issn = "0317-1671",

publisher = "Canadian Journal of Neurological Sciences",

number = "3",

}

TY - JOUR

T1 - Defining CT Perfusion Thresholds for Infarction in the Golden Hour and with Ultra-Early Reperfusion

AU - Najm, Mohamed

AU - Al-Ajlan, Fahad S.

AU - Boesen, Mari E.

AU - Hur, Lisa

AU - Kim, Chi Kyung

AU - Fainardi, Enrico

AU - Hill, Michael D.

AU - Demchuk, Andrew M.

AU - Goyal, Mayank

AU - Lee, Ting Y.

AU - Menon, Bijoy K.

PY - 2018/5/1

Y1 - 2018/5/1

N2 - In this brief report, computed tomography perfusion (CTP) thresholds predicting follow-up infarction in patients presenting <3 hours from stroke onset and achieving ultra-early reperfusion (<45 minutes from CTP) are reported. CTP thresholds that predict follow-up infarction vary based on time to reperfusion: Tmax >20 to 23 seconds and cerebral blood flow <5 to 7 ml/min -1 /(100 g) -1 or relative cerebral blood flow <0.14 to 0.20 optimally predicted the final infarct. These thresholds are stricter than published thresholds.

AB - In this brief report, computed tomography perfusion (CTP) thresholds predicting follow-up infarction in patients presenting <3 hours from stroke onset and achieving ultra-early reperfusion (<45 minutes from CTP) are reported. CTP thresholds that predict follow-up infarction vary based on time to reperfusion: Tmax >20 to 23 seconds and cerebral blood flow <5 to 7 ml/min -1 /(100 g) -1 or relative cerebral blood flow <0.14 to 0.20 optimally predicted the final infarct. These thresholds are stricter than published thresholds.

KW - CT perfusion

KW - early reperfusion

KW - endovascular therapy

UR - http://www.scopus.com/inward/record.url?scp=85047195542&partnerID=8YFLogxK

U2 - 10.1017/cjn.2017.287

DO - 10.1017/cjn.2017.287

M3 - Article

C2 - 29455683

AN - SCOPUS:85047195542

SN - 0317-1671

VL - 45

SP - 339

EP - 342

JO - Canadian Journal of Neurological Sciences

JF - Canadian Journal of Neurological Sciences

IS - 3

ER -

Defining CT Perfusion Thresholds for Infarction in the Golden Hour and with Ultra-Early Reperfusion

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this