Design of molecular two-photon probes for in vivo imaging. 2H-Benzo[h]chromene-2-one derivatives

Hwan Myung Kim; Xing Zhong Fang; Pil Rye Yang; Jae Sung Yi; Young Gyu Ko; Ming Jun Piao; Young Dae Chung; Young Woo Park; Seung Joon Jeon; Bong Rae Cho

doi:10.1016/j.tetlet.2007.01.176

Design of molecular two-photon probes for in vivo imaging. 2H-Benzo[h]chromene-2-one derivatives

Hwan Myung Kim, Xing Zhong Fang, Pil Rye Yang, Jae Sung Yi, Young Gyu Ko, Ming Jun Piao, Young Dae Chung, Young Woo Park, Seung Joon Jeon, Bong Rae Cho

Research output: Contribution to journal › Article › peer-review

55 Citations (Scopus)

Abstract

2H-Benzo[h]chromene-2-one derivatives showing appreciable water solubility, significant two-photon cross sections, high photostability, cell permeability, low toxicity, and ability to be converted to a protein TP probe have been developed by incorporating all of the needed functions within a small molecule.

Original language	English
Pages (from-to)	2791-2795
Number of pages	5
Journal	Tetrahedron Letters
Volume	48
Issue number	15
DOIs	https://doi.org/10.1016/j.tetlet.2007.01.176
Publication status	Published - 2007 Apr 9

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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title = "Design of molecular two-photon probes for in vivo imaging. 2H-Benzo[h]chromene-2-one derivatives",

abstract = "2H-Benzo[h]chromene-2-one derivatives showing appreciable water solubility, significant two-photon cross sections, high photostability, cell permeability, low toxicity, and ability to be converted to a protein TP probe have been developed by incorporating all of the needed functions within a small molecule.",

author = "Kim, {Hwan Myung} and Fang, {Xing Zhong} and Yang, {Pil Rye} and Yi, {Jae Sung} and Ko, {Young Gyu} and Piao, {Ming Jun} and Chung, {Young Dae} and Park, {Young Woo} and Jeon, {Seung Joon} and Cho, {Bong Rae}",

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T1 - Design of molecular two-photon probes for in vivo imaging. 2H-Benzo[h]chromene-2-one derivatives

AU - Kim, Hwan Myung

AU - Fang, Xing Zhong

AU - Yang, Pil Rye

AU - Yi, Jae Sung

AU - Ko, Young Gyu

AU - Piao, Ming Jun

AU - Chung, Young Dae

AU - Park, Young Woo

AU - Jeon, Seung Joon

AU - Cho, Bong Rae

PY - 2007/4/9

Y1 - 2007/4/9

N2 - 2H-Benzo[h]chromene-2-one derivatives showing appreciable water solubility, significant two-photon cross sections, high photostability, cell permeability, low toxicity, and ability to be converted to a protein TP probe have been developed by incorporating all of the needed functions within a small molecule.

AB - 2H-Benzo[h]chromene-2-one derivatives showing appreciable water solubility, significant two-photon cross sections, high photostability, cell permeability, low toxicity, and ability to be converted to a protein TP probe have been developed by incorporating all of the needed functions within a small molecule.

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 15

ER -

Design of molecular two-photon probes for in vivo imaging. 2H-Benzo[h]chromene-2-one derivatives

Abstract

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