Abstract
We herein report a fluorescence probe 1 capable of detecting water-soluble oligomeric Aβ aggregates and Aβ fibrils. Upon injection into Aβ42-challenged mouse brains, probe 1 shows increased fluorescence intensity, indicating its facile binding to extracellular Aβ fibrils in brain tissues.
Original language | English |
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Pages (from-to) | 5741-5744 |
Number of pages | 4 |
Journal | Chemical Communications |
Volume | 50 |
Issue number | 43 |
DOIs | |
Publication status | Published - 2014 May 1 |
ASJC Scopus subject areas
- Catalysis
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- Chemistry(all)
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry