TY - JOUR
T1 - Detection of metastatic cervical lymph nodes in recurrent papillary thyroid carcinoma
T2 - Computed tomography versus positron emission tomography-computed tomography
AU - Lee, Dong Hoon
AU - Kang, Won Jun
AU - Seo, Hyung Suk
AU - Kim, Eunhee
AU - Kim, Ji Hoon
AU - Son, Kyu Ri
AU - Na, Dong Gyu
PY - 2009
Y1 - 2009
N2 - OBJECTIVE: We sought to determine whether positron emission tomography-computed tomography (PET-CT) is more accurate than CT for detecting metastatic cervical lymph nodes in recurrent papillary thyroid carcinoma (PTC) and to determine the relationship between the CT features and PET-CT findings of metastatic nodes. METHODS: Eleven consecutive patients with recurrent PTC underwent contrast-enhanced CT (CECT) and PET-CT before surgery. We retrospectively evaluated CECT and PET-CT images to determine the presence of metastatic nodes by level-by-level analysis. The CT findings of the PET-CT results that were positive and negative for metastatic nodes were compared. RESULTS: Metastatic nodes were found at 28 (78%) of 36 neck levels surgically explored. The sensitivity, specificity, and accuracy of CECT for the detection of metastatic nodes were 75.0%, 87.5%, and 77.8%, respectively, and those of PET-CT were 35.7%, 87.5%, and 48.6%, respectively, by level-by-level analysis. No significant difference in the CT features was found between the PET-CT findings positive and negative for metastatic nodes (P > 0.05). CONCLUSIONS: Computed tomography is more sensitive and accurate than PET-CT for detecting metastatic lymph nodes in recurrent PTC. No significant relationship was found between the CT features and the PET-CT findings of the metastatic nodes.
AB - OBJECTIVE: We sought to determine whether positron emission tomography-computed tomography (PET-CT) is more accurate than CT for detecting metastatic cervical lymph nodes in recurrent papillary thyroid carcinoma (PTC) and to determine the relationship between the CT features and PET-CT findings of metastatic nodes. METHODS: Eleven consecutive patients with recurrent PTC underwent contrast-enhanced CT (CECT) and PET-CT before surgery. We retrospectively evaluated CECT and PET-CT images to determine the presence of metastatic nodes by level-by-level analysis. The CT findings of the PET-CT results that were positive and negative for metastatic nodes were compared. RESULTS: Metastatic nodes were found at 28 (78%) of 36 neck levels surgically explored. The sensitivity, specificity, and accuracy of CECT for the detection of metastatic nodes were 75.0%, 87.5%, and 77.8%, respectively, and those of PET-CT were 35.7%, 87.5%, and 48.6%, respectively, by level-by-level analysis. No significant difference in the CT features was found between the PET-CT findings positive and negative for metastatic nodes (P > 0.05). CONCLUSIONS: Computed tomography is more sensitive and accurate than PET-CT for detecting metastatic lymph nodes in recurrent PTC. No significant relationship was found between the CT features and the PET-CT findings of the metastatic nodes.
KW - CT
KW - Lymph node metastasis
KW - PET-CT
KW - Papillary thyroid cancer
UR - http://www.scopus.com/inward/record.url?scp=70349757173&partnerID=8YFLogxK
U2 - 10.1097/RCT.0b013e31818fb3f1
DO - 10.1097/RCT.0b013e31818fb3f1
M3 - Article
C2 - 19820516
AN - SCOPUS:70349757173
SN - 0363-8715
VL - 33
SP - 805
EP - 810
JO - Journal of Computer Assisted Tomography
JF - Journal of Computer Assisted Tomography
IS - 5
ER -