Determining correspondence in 3-D MR brain images using attribute vectors as morphological signatures of voxels

Zhong Xue, Dinggang Shen, Christos Davatzikos

    Research output: Contribution to journalArticlepeer-review

    55 Citations (Scopus)

    Abstract

    Finding point correspondence in anatomical images is a key step in shape analysis and deformable registration. This paper proposes an automatic correspondence detection algorithm for intramodality MR brain images of different subjects using wavelet-based attribute vectors (WAVs) denned on every image voxel. The attribute vector (AV) is extracted from the wavelet subimages and reflects the image structure in a large neighborhood around the respective voxel in a multiscale fashion. It plays the role of a morphological signature for each voxel, and our goal is, therefore, to make it distinctive of the respective voxel. Correspondence is then determined from similarities of AVs. By incorporating the prior knowledge of the spatial relationship among voxels, the ability of the proposed algorithm to find anatomical correspondence is further improved. Experiments with MR images of human brains show that the algorithm performs similarly to experts, even for complex cortical structures.

    Original languageEnglish
    Pages (from-to)1276-1291
    Number of pages16
    JournalIEEE Transactions on Medical Imaging
    Volume23
    Issue number10
    DOIs
    Publication statusPublished - 2004 Oct

    Bibliographical note

    Funding Information:
    Manuscript received May 2, 2004; revised June 24, 2004. This work was supported by the National Institutes of Health (NIH) under Grant R01AG14971. The Associate Editor responsible for coordinating the review of this paper and recommending its publication was M. Sonka. Asterisk indicates corresponding author. *Z. Xue is with the Section of Biomedical Image Analysis (SBIA), Department of Radiology School of Medicine, University of Pennsylvania, 3600 Market ST Suite 380, Philadelphia PA 19104 USA (e-mail: [email protected]).

    Keywords

    • Computational anatomy
    • Correspondence
    • Deformable registration
    • Image matching
    • Wavelet transformations

    ASJC Scopus subject areas

    • Software
    • Radiological and Ultrasound Technology
    • Computer Science Applications
    • Electrical and Electronic Engineering

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