Development and evaluation of a protein microarray chip for diagnosis of hepatitis C virus

Chul Soo Yuk; Ku Lee Hyung; Tae Kim Hee; Keel Choi Yong; Cheon Lee Byung; Bok Hwan Chun; Namhyun Chung

doi:10.1023/B:BILE.0000045653.92719.a4

Development and evaluation of a protein microarray chip for diagnosis of hepatitis C virus

Chul Soo Yuk, Ku Lee Hyung, Tae Kim Hee, Keel Choi Yong, Cheon Lee Byung, Bok Hwan Chun, Namhyun Chung

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

A protein chip diagnostic kit was developed for the diagnosis of hepatitis C virus (HCV) based on the protein chip technique and the immuno-concentration method. This kit was designed for low-density protein chips and also for the availability of multiple sample screening. Applicability of the chip was evaluated using 96 blood specimens and the results were compared to results of an anti-HCV enzyme immunoassay (EIA) test. With further development, the technology associated with the development of this chip could be applied to the simultaneous detection of multiple protein-protein, protein-ligand interactions.

Original language	English
Pages (from-to)	1563-1568
Number of pages	6
Journal	Biotechnology letters
Volume	26
Issue number	20
DOIs	https://doi.org/10.1023/B:BILE.0000045653.92719.a4
Publication status	Published - 2004 Oct

Keywords

Blood testing
Hepatitis C virus
Immuno-concentration
Membrane
Microarray
Protein array

ASJC Scopus subject areas

Biotechnology
Bioengineering
Applied Microbiology and Biotechnology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1023/B:BILE.0000045653.92719.a4

Cite this

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title = "Development and evaluation of a protein microarray chip for diagnosis of hepatitis C virus",

abstract = "A protein chip diagnostic kit was developed for the diagnosis of hepatitis C virus (HCV) based on the protein chip technique and the immuno-concentration method. This kit was designed for low-density protein chips and also for the availability of multiple sample screening. Applicability of the chip was evaluated using 96 blood specimens and the results were compared to results of an anti-HCV enzyme immunoassay (EIA) test. With further development, the technology associated with the development of this chip could be applied to the simultaneous detection of multiple protein-protein, protein-ligand interactions.",

keywords = "Blood testing, Hepatitis C virus, Immuno-concentration, Membrane, Microarray, Protein array",

author = "Yuk, {Chul Soo} and Hyung, {Ku Lee} and Hee, {Tae Kim} and Yong, {Keel Choi} and Byung, {Cheon Lee} and Chun, {Bok Hwan} and Namhyun Chung",

note = "Funding Information: This work was supported by a Technical Innovation Project of the Small and Medium Business Administration of Korea.",

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AU - Yuk, Chul Soo

AU - Hyung, Ku Lee

AU - Hee, Tae Kim

AU - Yong, Keel Choi

AU - Byung, Cheon Lee

AU - Chun, Bok Hwan

AU - Chung, Namhyun

N1 - Funding Information: This work was supported by a Technical Innovation Project of the Small and Medium Business Administration of Korea.

PY - 2004/10

Y1 - 2004/10

N2 - A protein chip diagnostic kit was developed for the diagnosis of hepatitis C virus (HCV) based on the protein chip technique and the immuno-concentration method. This kit was designed for low-density protein chips and also for the availability of multiple sample screening. Applicability of the chip was evaluated using 96 blood specimens and the results were compared to results of an anti-HCV enzyme immunoassay (EIA) test. With further development, the technology associated with the development of this chip could be applied to the simultaneous detection of multiple protein-protein, protein-ligand interactions.

AB - A protein chip diagnostic kit was developed for the diagnosis of hepatitis C virus (HCV) based on the protein chip technique and the immuno-concentration method. This kit was designed for low-density protein chips and also for the availability of multiple sample screening. Applicability of the chip was evaluated using 96 blood specimens and the results were compared to results of an anti-HCV enzyme immunoassay (EIA) test. With further development, the technology associated with the development of this chip could be applied to the simultaneous detection of multiple protein-protein, protein-ligand interactions.

KW - Blood testing

KW - Hepatitis C virus

KW - Immuno-concentration

KW - Membrane

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Development and evaluation of a protein microarray chip for diagnosis of hepatitis C virus

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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