Development and growth of the normal cranial vault: An embryologic review

Sung Won Jin, Ki Bum Sim, Sang Dae Kim

Research output: Contribution to journalReview articlepeer-review

86 Citations (Scopus)


Understanding the development of a skull deformity requires an understanding of the normal morphogenesis of the cranium. Craniosynostosis is the premature, pathologic ossification of one or more cranial sutures leading to skull deformities. A review of the English medical literature using textbooks and standard search engines was performed to gather information about the prenatal development and growth of the cranial vault of the neurocranium. A process of morphogenic sequencing begins during prenatal development and growth, continues postnatally, and contributes to the basis for the differential manner of growth of cranial vault bones. This improved knowledge might facilitate comprehension of the pathophysiology of craniosynostosis.

Original languageEnglish
Pages (from-to)192-196
Number of pages5
JournalJournal of Korean Neurosurgical Society
Issue number3
Publication statusPublished - 2016
Externally publishedYes


  • Cranial sutures
  • Craniosynostosis
  • Embryonic development
  • Growth
  • Skull

ASJC Scopus subject areas

  • Surgery
  • Neuroscience(all)
  • Clinical Neurology


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