Abstract
A nanoporous poly-(styrene sulfonate) (poly-SS) membrane was developed for fast and selective ion transport in a microfluidic chip. The poly-SS membrane can be photopolymerized in-situ at arbitrary location of a microchannel, enabling integrated fluidics design in the microfluidic chip. The membrane is characterized by a low hydraulic resistance and a high surface charge to maximize the electroosmotic flow and charge selectivity. The membrane characteristics were investigated by charge-selective electropreconcentration method. Experimental results show membranes with various percentages of poly-SS are able to concentrate anions (fluorescein and TRITC-labeled BSA). The anion-selective electropreconcentration process is stable and 26-times faster than previously reported poly-AMPS (2-acrylamido-2-methyl-1-propanesulfonic acid) based system. The electropreconcentration was also demonstrated to depend on the sample valency and buffer concentration.
| Original language | English |
|---|---|
| Pages (from-to) | 2181-2187 |
| Number of pages | 7 |
| Journal | Electrophoresis |
| Volume | 39 |
| Issue number | 17 |
| DOIs | |
| Publication status | Published - 2018 Sept |
Bibliographical note
Publisher Copyright:© 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Keywords
- Electropreconcentration
- Ion concentration polarization
- Ion exchange membrane
- Iontronics
- Microfluidics
- Poly-SS
ASJC Scopus subject areas
- Biochemistry
- Clinical Biochemistry
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