Development of a novel fluorescence probe capable of assessing the cytoplasmic entry of siderophore-based conjugates

Hyeon Seok Kim; Woon Young Song; Hak Joong Kim

doi:10.1039/c4ob01810a

Development of a novel fluorescence probe capable of assessing the cytoplasmic entry of siderophore-based conjugates

Hyeon Seok Kim, Woon Young Song, Hak Joong Kim

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

A novel fluorescence probe capable of assessing the cytoplasmic entry of siderophore-based conjugates was synthesized and evaluated by photochemical characterization and cell-based assays. The specific responsiveness to the cytoplasmic entry of the probe was implemented by adopting a disulfide linker, whose cleavage under the reducing conditions of the cytoplasm induced the display of a distinctive fluorescence signal. This journal is

Original language	English
Pages (from-to)	73-76
Number of pages	4
Journal	Organic and Biomolecular Chemistry
Volume	13
Issue number	1
DOIs	https://doi.org/10.1039/c4ob01810a
Publication status	Published - 2015 Jan 7

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1039/c4ob01810a

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abstract = "A novel fluorescence probe capable of assessing the cytoplasmic entry of siderophore-based conjugates was synthesized and evaluated by photochemical characterization and cell-based assays. The specific responsiveness to the cytoplasmic entry of the probe was implemented by adopting a disulfide linker, whose cleavage under the reducing conditions of the cytoplasm induced the display of a distinctive fluorescence signal. This journal is",

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AU - Song, Woon Young

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Development of a novel fluorescence probe capable of assessing the cytoplasmic entry of siderophore-based conjugates

Abstract

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