Abstract
We designed a novel single-photon emission computed tomography (SPECT) system with a variable pinhole (VP) collimator for obtaining high-sensitivity and high-spatial resolution imaging of a region of interest (ROI). Extending the capabilities of conventional SPECT systems, this novel SPECT system with a VP collimator can adjust its driving parameters, such as a collimator diameter, acceptance angle, and distances between the ROI, collimator, and detector at different rotation angles. Previously, we simulated a VP collimator and demonstrated the superiority of the VP SPECT system in terms of its sensitivity and spatial resolution. Based on these previous results, we developed a prototype SPECT system for performance evaluation of a VP collimator. The collimator was made from 99.9% pure tungsten layers, with 16 holes of different diameters. The area of the CsI(Tl) scintillator was 45.7 × 45.7 mm2 (51 × 51 pixels), with pixel dimensions of 0.7 × 0.7 × 5 mm2. The multi-pixel photon counter was tiled into a 2 × 2 configuration with dimensions of 52 × 52 mm2. The collimator, detector, and gantry of this SPECT system were independently controlled. We acquired initial reconstructed images from a point source (Co-57) and an ultra-micro phantom (Tc-99m). The point source and the phantom were clearly resolved, demonstrating satisfactory detector response, signal processing, and imaging processing capabilities. The 1.35mm phantom was also clearly resolved in the ultra-micro phantom.
Original language | English |
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Title of host publication | 2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop, NSS/MIC/RTSD 2016 |
Publisher | Institute of Electrical and Electronics Engineers Inc. |
Volume | 2017-January |
ISBN (Electronic) | 9781509016426 |
DOIs | |
Publication status | Published - 2017 Oct 16 |
Event | 2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop, NSS/MIC/RTSD 2016 - Strasbourg, France Duration: 2016 Oct 29 → 2016 Nov 6 |
Other
Other | 2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop, NSS/MIC/RTSD 2016 |
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Country/Territory | France |
City | Strasbourg |
Period | 16/10/29 → 16/11/6 |
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Instrumentation
- Nuclear and High Energy Physics
- Electronic, Optical and Magnetic Materials