Development of a rectally administrable Dnase1 to treat septic shock by targeting NETs

Immunology and Microbiology

• Neutrophil Extracellular Traps 100%
• Absorption 50%
• Vein 50%
• Mouse Model 50%
• Survival Rate 50%
• Mortality Rate 50%
• Neutrophil 50%
• Systemic Inflammation 50%
• Rectum 50%
• Rectum Mucosa 50%
• Peptides 50%
• Amino Acid 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Septic Shock 100%
• Rectal Administration 60%
• Deoxyribonuclease 40%
• Amino Acid 20%
• Inflammation 20%
• Mortality Rate 20%
• Survival Rate 20%
• Mouse Model 20%
• Hypotension 20%
• Enzymes 20%
• Cell Penetrating Peptide 20%

Keyphrases

• Mouse Rectum 20%