Development of a screening method for health Hazard ranking and scoring of chemicals using the Mahalanobis–Taguchi system

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10 Citations (Scopus)


For efficient management of chemicals, it is necessary to preferentially select hazardous chemicals as being high-priority through a screening method. Over the past 20 years, chemical ranking and scoring (CRS) methods have been applied in many countries; however, these CRS methods have a few limitations. Most of the existing methods only use some of the variables to calculate the hazard of chemicals or use the most conservative score without consideration of the correlation between chemical toxicities. This evaluation could underestimate or overestimate the real health hazard of the chemicals. To overcome the limitations of these methods, we developed a new CRS method using the Mahalanobis–Taguchi System (MTS). The MTS, which conducts multivariate analysis, produced chemical rankings that took into accounts the correlation between variables related to chemical health hazards. Also, the proportion of chemicals managed by the Korea Chemicals Control Act that were given a high rating appeared to be higher when the MTS was used, compared to the existing methods. These results indicated that the new method evaluated the health hazards of chemicals more accurately, and we expect that the MTS method could be applied to a greater range of chemicals than the existing CRS methods.

Original languageEnglish
Article number2208
JournalInternational journal of environmental research and public health
Issue number10
Publication statusPublished - 2018 Oct 10

Bibliographical note

Publisher Copyright:
© 2018 by the authors. Licensee MDPI, Basel, Switzerland.


  • Chemical ranking and scoring
  • Mahalanobis-Taguchi system
  • Priority setting

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Pollution
  • Health, Toxicology and Mutagenesis


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