Abstract
In this work, we fabricated the microfluidic chip-based micro-alginate tubes (MAT) for angiogenesis. These micro-alginate tubes could be adjusted in selfdeveloping extracellular matrix (ECM)-like networks. We have used poly(dimethylsiloxane) (PDMS) microfluidic device integrated capillary glass pipette as apparatus for micro-alginate tube generation. In addition, we evaluated the micro-alginate tube as an angiogenesis by loading calf pulmonary artery endothelial (CPAE) cells during the fabrication MHT process. From the LIVE/DEAD assay, CPAE cells survived well during the 5 days in vitro. The microfluidic chip-based micro-alginate tube, including cells or proteins, can be produced effective 3-D shaped micro-vascular for the angiogenesis.
| Original language | English |
|---|---|
| Title of host publication | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences - The Proceedings of MicroTAS 2008 Conference |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 525-527 |
| Number of pages | 3 |
| Publication status | Published - 2008 |
| Event | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States Duration: 2008 Oct 12 → 2008 Oct 16 |
Other
| Other | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 |
|---|---|
| Country/Territory | United States |
| City | San Diego, CA |
| Period | 08/10/12 → 08/10/16 |
Keywords
- Alginate
- Angiogenesis
- Microtube
ASJC Scopus subject areas
- Chemical Engineering (miscellaneous)
- Bioengineering