Development of prediction equation of diffusing capacity of lung for koreans

Yong Il Hwang; Yong Bum Park; Hyoung Kyu Yoon; Seong Yong Lim; Tae Hyung Kim; Joo Hun Park; Won Yeon Lee; Seong Ju Park; Sei Won Lee; Woo Jin Kim; Ki Uk Kim; Kyeong Cheol Shin; Do Jin Kim; Hui Jung Kim; Tae Eun Kim; Kwang Ha Yoo; Jae Jeong Shim

doi:10.4046/trd.2017.0118

Development of prediction equation of diffusing capacity of lung for koreans

Yong Il Hwang, Yong Bum Park, Hyoung Kyu Yoon, Seong Yong Lim, Tae Hyung Kim, Joo Hun Park, Won Yeon Lee, Seong Ju Park, Sei Won Lee, Woo Jin Kim, Ki Uk Kim, Kyeong Cheol Shin, Do Jin Kim, Hui Jung Kim, Tae Eun Kim, Kwang Ha Yoo, Jae Jeong Shim

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Background: The diffusing capacity of the lung is influenced by multiple factors such as age, sex, height, weight, ethnicity and smoking status. Although a prediction equation for the diffusing capacity of Korea was proposed in the mid-1980s, this equation is not used currently. The aim of this study was to develop a new prediction equation for the diffusing capacity for Koreans. Methods: Using the data of the Korean National Health and Nutrition Examination Survey, a total of 140 nonsmokers with normal chest X-rays were enrolled in this study. Results: Using linear regression analysis, a new predicting equation for diffusing capacity was developed. For men, the following new equations were developed: carbon monoxide diffusing capacity (DLco)=–10.4433–0.1434×age (year)+0.2482×heights (cm); DLco/alveolar volume (VA)=6.01507–0.02374×age (year)–0.00233×heights (cm). For women the prediction equations were described as followed: DLco=–12.8895–0.0532×age (year)+0.2145×heights (cm) and DLco/VA=7.69516–0.02219×age (year)–0.01377×heights (cm). All equations were internally validated by k-fold cross validation method. Conclusion: In this study, we developed new prediction equations for the diffusing capacity of the lungs of Koreans. A further study is needed to validate the new predicting equation for diffusing capacity.

Original language	English
Pages (from-to)	42-48
Number of pages	7
Journal	Tuberculosis and Respiratory Diseases
Volume	81
Issue number	1
DOIs	https://doi.org/10.4046/trd.2017.0118
Publication status	Published - 2018 Jan

Bibliographical note

Publisher Copyright:
Copyright © 2018 The Korean Academy of Tuberculosis and Respiratory Diseases. All rights reserved.

Keywords

Carbon Monoxide
Diffusion
Korean
Pulmonary Diffusing Capacity

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.4046/trd.2017.0118

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Hwang, Y. I., Park, Y. B., Yoon, H. K., Lim, S. Y., Kim, T. H., Park, J. H., Lee, W. Y., Park, S. J., Lee, S. W., Kim, W. J., Kim, K. U., Shin, K. C., Kim, D. J., Kim, H. J., Kim, T. E., Yoo, K. H., & Shim, J. J. (2018). Development of prediction equation of diffusing capacity of lung for koreans. Tuberculosis and Respiratory Diseases, 81(1), 42-48. https://doi.org/10.4046/trd.2017.0118

@article{888b65a766d242f18f3600cacfbc71bd,

title = "Development of prediction equation of diffusing capacity of lung for koreans",

abstract = "Background: The diffusing capacity of the lung is influenced by multiple factors such as age, sex, height, weight, ethnicity and smoking status. Although a prediction equation for the diffusing capacity of Korea was proposed in the mid-1980s, this equation is not used currently. The aim of this study was to develop a new prediction equation for the diffusing capacity for Koreans. Methods: Using the data of the Korean National Health and Nutrition Examination Survey, a total of 140 nonsmokers with normal chest X-rays were enrolled in this study. Results: Using linear regression analysis, a new predicting equation for diffusing capacity was developed. For men, the following new equations were developed: carbon monoxide diffusing capacity (DLco)=–10.4433–0.1434×age (year)+0.2482×heights (cm); DLco/alveolar volume (VA)=6.01507–0.02374×age (year)–0.00233×heights (cm). For women the prediction equations were described as followed: DLco=–12.8895–0.0532×age (year)+0.2145×heights (cm) and DLco/VA=7.69516–0.02219×age (year)–0.01377×heights (cm). All equations were internally validated by k-fold cross validation method. Conclusion: In this study, we developed new prediction equations for the diffusing capacity of the lungs of Koreans. A further study is needed to validate the new predicting equation for diffusing capacity.",

keywords = "Carbon Monoxide, Diffusion, Korean, Pulmonary Diffusing Capacity",

author = "Hwang, {Yong Il} and Park, {Yong Bum} and Yoon, {Hyoung Kyu} and Lim, {Seong Yong} and Kim, {Tae Hyung} and Park, {Joo Hun} and Lee, {Won Yeon} and Park, {Seong Ju} and Lee, {Sei Won} and Kim, {Woo Jin} and Kim, {Ki Uk} and Shin, {Kyeong Cheol} and Kim, {Do Jin} and Kim, {Hui Jung} and Kim, {Tae Eun} and Yoo, {Kwang Ha} and Shim, {Jae Jeong}",

year = "2018",

month = jan,

doi = "10.4046/trd.2017.0118",

language = "English",

volume = "81",

pages = "42--48",

journal = "Tuberculosis and Respiratory Diseases",

issn = "1738-3536",

publisher = "The Korean Academy of Tuberculosis and Respiratory Diseases",

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T1 - Development of prediction equation of diffusing capacity of lung for koreans

AU - Hwang, Yong Il

AU - Park, Yong Bum

AU - Yoon, Hyoung Kyu

AU - Lim, Seong Yong

AU - Kim, Tae Hyung

AU - Park, Joo Hun

AU - Lee, Won Yeon

AU - Park, Seong Ju

AU - Lee, Sei Won

AU - Kim, Woo Jin

AU - Kim, Ki Uk

AU - Shin, Kyeong Cheol

AU - Kim, Do Jin

AU - Kim, Hui Jung

AU - Kim, Tae Eun

AU - Yoo, Kwang Ha

AU - Shim, Jae Jeong

PY - 2018/1

Y1 - 2018/1

N2 - Background: The diffusing capacity of the lung is influenced by multiple factors such as age, sex, height, weight, ethnicity and smoking status. Although a prediction equation for the diffusing capacity of Korea was proposed in the mid-1980s, this equation is not used currently. The aim of this study was to develop a new prediction equation for the diffusing capacity for Koreans. Methods: Using the data of the Korean National Health and Nutrition Examination Survey, a total of 140 nonsmokers with normal chest X-rays were enrolled in this study. Results: Using linear regression analysis, a new predicting equation for diffusing capacity was developed. For men, the following new equations were developed: carbon monoxide diffusing capacity (DLco)=–10.4433–0.1434×age (year)+0.2482×heights (cm); DLco/alveolar volume (VA)=6.01507–0.02374×age (year)–0.00233×heights (cm). For women the prediction equations were described as followed: DLco=–12.8895–0.0532×age (year)+0.2145×heights (cm) and DLco/VA=7.69516–0.02219×age (year)–0.01377×heights (cm). All equations were internally validated by k-fold cross validation method. Conclusion: In this study, we developed new prediction equations for the diffusing capacity of the lungs of Koreans. A further study is needed to validate the new predicting equation for diffusing capacity.

AB - Background: The diffusing capacity of the lung is influenced by multiple factors such as age, sex, height, weight, ethnicity and smoking status. Although a prediction equation for the diffusing capacity of Korea was proposed in the mid-1980s, this equation is not used currently. The aim of this study was to develop a new prediction equation for the diffusing capacity for Koreans. Methods: Using the data of the Korean National Health and Nutrition Examination Survey, a total of 140 nonsmokers with normal chest X-rays were enrolled in this study. Results: Using linear regression analysis, a new predicting equation for diffusing capacity was developed. For men, the following new equations were developed: carbon monoxide diffusing capacity (DLco)=–10.4433–0.1434×age (year)+0.2482×heights (cm); DLco/alveolar volume (VA)=6.01507–0.02374×age (year)–0.00233×heights (cm). For women the prediction equations were described as followed: DLco=–12.8895–0.0532×age (year)+0.2145×heights (cm) and DLco/VA=7.69516–0.02219×age (year)–0.01377×heights (cm). All equations were internally validated by k-fold cross validation method. Conclusion: In this study, we developed new prediction equations for the diffusing capacity of the lungs of Koreans. A further study is needed to validate the new predicting equation for diffusing capacity.

KW - Carbon Monoxide

KW - Diffusion

KW - Korean

KW - Pulmonary Diffusing Capacity

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DO - 10.4046/trd.2017.0118

M3 - Article

AN - SCOPUS:85041528320

SN - 1738-3536

VL - 81

SP - 42

EP - 48

JO - Tuberculosis and Respiratory Diseases

JF - Tuberculosis and Respiratory Diseases

IS - 1

ER -

Development of prediction equation of diffusing capacity of lung for koreans

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

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