Dihydroxylation of 2-vinylaziridine: Efficient synthesis of D-ribo-phytosphingosine

Hyo Jae Yoon, Yong Woo Kim, Baeck Kyoung Lee, Won Koo Lee, Yongeun Kim, Hyun Joon Ha

Research output: Contribution to journalArticlepeer-review

48 Citations (Scopus)


An efficient and highly stereoselective synthesis of D-ribo-(2S,3S,4R)- phytosphingosine was accomplished in 62% overall yield starting from commercially available (2S)-hydroxymethylaziridine via osmium-catalyzed asymmetric dihydroxylation as a key step.

Original languageEnglish
Pages (from-to)79-81
Number of pages3
JournalChemical Communications
Issue number1
Publication statusPublished - 2007
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry


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