Direct measurement of the dielectrophoresis forces acting on micro-objects using optical tweezers and a simple microfluidic chip

In Soo Park; Se Hee Park; Dae Sung Yoon; Sang Woo Lee; Beop Min Kim

doi:10.1063/1.4895115

Direct measurement of the dielectrophoresis forces acting on micro-objects using optical tweezers and a simple microfluidic chip

In Soo Park, Se Hee Park, Dae Sung Yoon, Sang Woo Lee, Beop Min Kim

School of Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

We constructed a reliable frequency-dependent dielectrophoretic (DEP) force measurement system based on optical tweezers and a microfluidic chip. Using this system, we directly measured the frequency-dependent DEP forces acting on polystyrene beads while varying various parameters, which were all verified by theoretical simulations. We also investigated the DEP characteristics of non-functionalized and carboxyl-functionalized polystyrene beads in solutions with different conductivities by associating the measured crossover frequencies with a theoretical DEP model. This system can be used as a quantifying tool for surface conductance assays by characterizing the DEP forces acting on micro-objects in various experimental conditions.

Original language	English
Article number	103701
Journal	Applied Physics Letters
Volume	105
Issue number	10
DOIs	https://doi.org/10.1063/1.4895115
Publication status	Published - 2014 Sept 8

Bibliographical note

Publisher Copyright:
© 2014 AIP Publishing LLC.

ASJC Scopus subject areas

Physics and Astronomy (miscellaneous)

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10.1063/1.4895115

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title = "Direct measurement of the dielectrophoresis forces acting on micro-objects using optical tweezers and a simple microfluidic chip",

abstract = "We constructed a reliable frequency-dependent dielectrophoretic (DEP) force measurement system based on optical tweezers and a microfluidic chip. Using this system, we directly measured the frequency-dependent DEP forces acting on polystyrene beads while varying various parameters, which were all verified by theoretical simulations. We also investigated the DEP characteristics of non-functionalized and carboxyl-functionalized polystyrene beads in solutions with different conductivities by associating the measured crossover frequencies with a theoretical DEP model. This system can be used as a quantifying tool for surface conductance assays by characterizing the DEP forces acting on micro-objects in various experimental conditions.",

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AU - Park, In Soo

AU - Park, Se Hee

AU - Yoon, Dae Sung

AU - Lee, Sang Woo

AU - Kim, Beop Min

PY - 2014/9/8

Y1 - 2014/9/8

N2 - We constructed a reliable frequency-dependent dielectrophoretic (DEP) force measurement system based on optical tweezers and a microfluidic chip. Using this system, we directly measured the frequency-dependent DEP forces acting on polystyrene beads while varying various parameters, which were all verified by theoretical simulations. We also investigated the DEP characteristics of non-functionalized and carboxyl-functionalized polystyrene beads in solutions with different conductivities by associating the measured crossover frequencies with a theoretical DEP model. This system can be used as a quantifying tool for surface conductance assays by characterizing the DEP forces acting on micro-objects in various experimental conditions.

AB - We constructed a reliable frequency-dependent dielectrophoretic (DEP) force measurement system based on optical tweezers and a microfluidic chip. Using this system, we directly measured the frequency-dependent DEP forces acting on polystyrene beads while varying various parameters, which were all verified by theoretical simulations. We also investigated the DEP characteristics of non-functionalized and carboxyl-functionalized polystyrene beads in solutions with different conductivities by associating the measured crossover frequencies with a theoretical DEP model. This system can be used as a quantifying tool for surface conductance assays by characterizing the DEP forces acting on micro-objects in various experimental conditions.

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Direct measurement of the dielectrophoresis forces acting on micro-objects using optical tweezers and a simple microfluidic chip

Abstract

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