Directing transition metal-based oxygen-functionalization catalysis

Gracita M. Tomboc, Yeji Park, Kwangyeol Lee, Kyoungsuk Jin

Research output: Contribution to journalReview articlepeer-review

6 Citations (Scopus)


This review presents the recent progress of oxygen functionalization reactions based on non-electrochemical (conventional organic synthesis) and electrochemical methods. Although both methods have their advantages and limitations, the former approach has been used to synthesize a broader range of organic substances as the latter is limited by several factors, such as poor selectivity and high energy cost. However, because electrochemical methods can replace harmful terminal oxidizers with external voltage, organic electrosynthesis has emerged as greener and more eco-friendly compared to conventional organic synthesis. The progress of electrochemical methods toward oxygen functionalization is presented by an in-depth discussion of different types of electrically driven-chemical organic synthesis, with particular attention to recently developed electrochemical systems and catalyst designs. We hope to direct the attention of readers to the latest breakthroughs of traditional oxygen functionalization reactions and to the potential of electrochemistry for the transformation of organic substrates to useful end products.

Original languageEnglish
Pages (from-to)8967-8995
Number of pages29
JournalChemical Science
Issue number26
Publication statusPublished - 2021 Jul 14

ASJC Scopus subject areas

  • Chemistry(all)


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