Discovery of a benzo[e]pyrimido-[5,4-b][1,4]diazepin-6(11H)-one as a potent and selective inhibitor of big MAP kinase 1

Xianming Deng, Qingkai Yang, Nicholas Kwiatkowski, Taebo Sim, Ultan McDermott, Jeffrey E. Settleman, Jiing Dwan Lee, Nathanael S. Gray

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    Chemistry

    Pharmacology, Toxicology and Pharmaceutical Science

    Biochemistry, Genetics and Molecular Biology