TY - JOUR
T1 - Disease burden of herpes zoster in Korea
AU - Choi, Won Suk
AU - Noh, Ji Yun
AU - Huh, Joong Yeon
AU - Jo, Yu Mi
AU - Lee, Jacob
AU - Song, Joon Young
AU - Kim, Woo Joo
AU - Cheong, Hee Jin
PY - 2010/4
Y1 - 2010/4
N2 - Background: The occurrence of herpes zoster can deteriorate the quality of life considerably, resulting in high disease burden. While Korea is assumed to have high disease burden of herpes zoster, there has been no researches analyzing this. Objectives: We performed this study to investigate the disease burden of herpes zoster in the Korean population as a whole. Study design: We used the database of the Health Insurance Review & Assessment Service of Korea and analyzed the data of patients who had herpes zoster as a principal diagnosis during the period from 2003 to 2007. We investigated the annual prevalence, rate of clinical visits, rate of hospitalization, and the pattern of medical services use. The socioeconomic burden of herpes zoster was calculated by a conversion into cost. Results: Rates of clinic visits and hospitalizations due to herpes zoster during the 5-year period from 2003 to 2007 were 7.93-12.54 per 1000 population and 0.22-0.32 per 1000 population, respectively. Prevalence rates according to age increased sharply after 50 years and reached a peak at 70 years. The total socioeconomic cost of herpes zoster was $75.9-143.8 million per year, increasing every year by 14-20%. Conclusions: There is a heavy socioeconomic burden due to herpes zoster in Korea and indicate that appropriate policies need to be established to reduce this burden. Additional researches are also necessary to assess the safety, efficacy and cost-effectiveness of a herpes zoster vaccine in the Korean population.
AB - Background: The occurrence of herpes zoster can deteriorate the quality of life considerably, resulting in high disease burden. While Korea is assumed to have high disease burden of herpes zoster, there has been no researches analyzing this. Objectives: We performed this study to investigate the disease burden of herpes zoster in the Korean population as a whole. Study design: We used the database of the Health Insurance Review & Assessment Service of Korea and analyzed the data of patients who had herpes zoster as a principal diagnosis during the period from 2003 to 2007. We investigated the annual prevalence, rate of clinical visits, rate of hospitalization, and the pattern of medical services use. The socioeconomic burden of herpes zoster was calculated by a conversion into cost. Results: Rates of clinic visits and hospitalizations due to herpes zoster during the 5-year period from 2003 to 2007 were 7.93-12.54 per 1000 population and 0.22-0.32 per 1000 population, respectively. Prevalence rates according to age increased sharply after 50 years and reached a peak at 70 years. The total socioeconomic cost of herpes zoster was $75.9-143.8 million per year, increasing every year by 14-20%. Conclusions: There is a heavy socioeconomic burden due to herpes zoster in Korea and indicate that appropriate policies need to be established to reduce this burden. Additional researches are also necessary to assess the safety, efficacy and cost-effectiveness of a herpes zoster vaccine in the Korean population.
KW - Disease burden
KW - Herpes zoster
KW - Varicella zoster virus
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U2 - 10.1016/j.jcv.2010.01.003
DO - 10.1016/j.jcv.2010.01.003
M3 - Article
C2 - 20181512
AN - SCOPUS:77949491655
SN - 1386-6532
VL - 47
SP - 325
EP - 329
JO - Journal of Clinical Virology
JF - Journal of Clinical Virology
IS - 4
ER -