Disruptions in resting state functional connectivity in euthymic bipolar patients with insomnia symptoms

Ho Kyoung Yoon, Sheena I. Dev, Ashley N. Sutherland, Lisa T. Eyler

    Research output: Contribution to journalArticlepeer-review

    3 Citations (Scopus)

    Abstract

    Insomnia is prevalent in bipolar disorder (BD) even during periods of euthymic mood. We compared resting state brain activity and cognitive function between euthymic BD with and without insomnia, and secondarily to healthy individuals. BD patients with insomnia symptoms showed a significantly lower functional connectivity within the task-positive network, compared to those without insomnia. They also showed significantly slower cognitive processing speed. These two features of BD with insomnia appeared relatively independent of each other. Preliminary findings suggest that exploration of the mechanisms of sleep disturbance in BD could lead to improved understanding and treatment of inattention in BD.

    Original languageEnglish
    Pages (from-to)1-4
    Number of pages4
    JournalPsychiatry Research - Neuroimaging
    Volume275
    DOIs
    Publication statusPublished - 2018 May 30

    Bibliographical note

    Publisher Copyright:
    © 2018 Elsevier B.V.

    Keywords

    • Bipolar disorder
    • Insomnia
    • Resting state

    ASJC Scopus subject areas

    • Neuroscience (miscellaneous)
    • Radiology Nuclear Medicine and imaging
    • Psychiatry and Mental health

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