Divergent ancestral lineages of newfound hantaviruses harbored by phylogenetically related crocidurine shrew species in Korea

Satoru Arai; Se Hun Gu; Luck Ju Baek; Kenji Tabara; Shannon N. Bennett; Hong Shik Oh; Nobuhiro Takada; Hae Ji Kang; Keiko Tanaka-Taya; Shigeru Morikawa; Nobuhiko Okabe; Richard Yanagihara; Jin Won Song

doi:10.1016/j.virol.2011.11.013

Divergent ancestral lineages of newfound hantaviruses harbored by phylogenetically related crocidurine shrew species in Korea

Satoru Arai, Se Hun Gu, Luck Ju Baek, Kenji Tabara, Shannon N. Bennett, Hong Shik Oh, Nobuhiro Takada, Hae Ji Kang, Keiko Tanaka-Taya, Shigeru Morikawa, Nobuhiko Okabe, Richard Yanagihara, Jin Won Song

Department of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

52 Citations (Scopus)

Abstract

Spurred by the recent isolation of a novel hantavirus, named Imjin virus (MJNV), from the Ussuri white-toothed shrew (Crocidura lasiura), targeted trapping was conducted for the phylogenetically related Asian lesser white-toothed shrew (Crocidura shantungensis). Pair-wise alignment and comparison of the S, M and L segments of a newfound hantavirus, designated Jeju virus (JJUV), indicated remarkably low nucleotide and amino acid sequence similarity with MJNV. Phylogenetic analyses, using maximum likelihood and Bayesian methods, showed divergent ancestral lineages for JJUV and MJNV, despite the close phylogenetic relationship of their reservoir soricid hosts. Also, no evidence of host switching was apparent in tanglegrams, generated by TreeMap 2.0β.

Original language	English
Pages (from-to)	99-105
Number of pages	7
Journal	Virology
Volume	424
Issue number	2
DOIs	https://doi.org/10.1016/j.virol.2011.11.013
Publication status	Published - 2012 Mar 15

Bibliographical note

Funding Information:
We thank Satoshi D. Ohdachi for helpful suggestions. This research was supported in part by a Grant-in-Aid Research on Emerging and Re-emerging Infectious Diseases, Health Labour Sciences Research Grant in Japan (H22-Shinko-Ippan-006), by the International Cooperative Research (no. 19406008 ) from the Japan Society for the Promotion of Science, by the Korean Ministry of Environment as “The Eco-technopia 21 project”, and by Institute of Biomedical Science & Food Safety, Korea University . Also, support was provided by the U.S. Public Health Service grants R01AI075057 from the National Institute of Allergy and Infectious Diseases and P20RR018727 (Centers of Biomedical Research Excellence) and G12RR003061 (Research Centers in Minority Institutions) from the National Center for Research Resources, National Institutes of Health .

Keywords

Crocidura
Hantavirus
Jeju Island
Korea
Phylogeny
Shrews

ASJC Scopus subject areas

Virology

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Arai, S., Gu, S. H., Baek, L. J., Tabara, K., Bennett, S. N., Oh, H. S., Takada, N., Kang, H. J., Tanaka-Taya, K., Morikawa, S., Okabe, N., Yanagihara, R., & Song, J. W. (2012). Divergent ancestral lineages of newfound hantaviruses harbored by phylogenetically related crocidurine shrew species in Korea. Virology, 424(2), 99-105. https://doi.org/10.1016/j.virol.2011.11.013

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title = "Divergent ancestral lineages of newfound hantaviruses harbored by phylogenetically related crocidurine shrew species in Korea",

abstract = "Spurred by the recent isolation of a novel hantavirus, named Imjin virus (MJNV), from the Ussuri white-toothed shrew (Crocidura lasiura), targeted trapping was conducted for the phylogenetically related Asian lesser white-toothed shrew (Crocidura shantungensis). Pair-wise alignment and comparison of the S, M and L segments of a newfound hantavirus, designated Jeju virus (JJUV), indicated remarkably low nucleotide and amino acid sequence similarity with MJNV. Phylogenetic analyses, using maximum likelihood and Bayesian methods, showed divergent ancestral lineages for JJUV and MJNV, despite the close phylogenetic relationship of their reservoir soricid hosts. Also, no evidence of host switching was apparent in tanglegrams, generated by TreeMap 2.0β.",

keywords = "Crocidura, Hantavirus, Jeju Island, Korea, Phylogeny, Shrews",

author = "Satoru Arai and Gu, {Se Hun} and Baek, {Luck Ju} and Kenji Tabara and Bennett, {Shannon N.} and Oh, {Hong Shik} and Nobuhiro Takada and Kang, {Hae Ji} and Keiko Tanaka-Taya and Shigeru Morikawa and Nobuhiko Okabe and Richard Yanagihara and Song, {Jin Won}",

note = "Funding Information: We thank Satoshi D. Ohdachi for helpful suggestions. This research was supported in part by a Grant-in-Aid Research on Emerging and Re-emerging Infectious Diseases, Health Labour Sciences Research Grant in Japan (H22-Shinko-Ippan-006), by the International Cooperative Research (no. 19406008 ) from the Japan Society for the Promotion of Science, by the Korean Ministry of Environment as “The Eco-technopia 21 project”, and by Institute of Biomedical Science & Food Safety, Korea University . Also, support was provided by the U.S. Public Health Service grants R01AI075057 from the National Institute of Allergy and Infectious Diseases and P20RR018727 (Centers of Biomedical Research Excellence) and G12RR003061 (Research Centers in Minority Institutions) from the National Center for Research Resources, National Institutes of Health .",

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AU - Tabara, Kenji

AU - Bennett, Shannon N.

AU - Oh, Hong Shik

AU - Takada, Nobuhiro

AU - Kang, Hae Ji

AU - Tanaka-Taya, Keiko

AU - Morikawa, Shigeru

AU - Okabe, Nobuhiko

AU - Yanagihara, Richard

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N2 - Spurred by the recent isolation of a novel hantavirus, named Imjin virus (MJNV), from the Ussuri white-toothed shrew (Crocidura lasiura), targeted trapping was conducted for the phylogenetically related Asian lesser white-toothed shrew (Crocidura shantungensis). Pair-wise alignment and comparison of the S, M and L segments of a newfound hantavirus, designated Jeju virus (JJUV), indicated remarkably low nucleotide and amino acid sequence similarity with MJNV. Phylogenetic analyses, using maximum likelihood and Bayesian methods, showed divergent ancestral lineages for JJUV and MJNV, despite the close phylogenetic relationship of their reservoir soricid hosts. Also, no evidence of host switching was apparent in tanglegrams, generated by TreeMap 2.0β.

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Divergent ancestral lineages of newfound hantaviruses harbored by phylogenetically related crocidurine shrew species in Korea

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

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