Droplet-based magnetically activated cell separator (DMACS): Evaluation of separation efficiency versus variance of magnetic flux density

Youngho Kim; Su Hong; Sang Ho Lee; Kyeongkap Paek; Byungkyu Kim

doi:10.1109/ICSENS.2007.355744

Droplet-based magnetically activated cell separator (DMACS): Evaluation of separation efficiency versus variance of magnetic flux density

Youngho Kim, Su Hong, Sang Ho Lee, Kyeongkap Paek, Byungkyu Kim

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

We introduced a droplet-based magnetically activated cell separator (DMACS) that utilizes a hanging droplet of microliter-sized volume for dividing positive (magnetically labeled) and negative (magnetically unlabeled) cells. It enabled us to solve adhesion problem in channel and showed better separation efficiency. However, the separation efficiency was changed under variations of initial volume (the droplet volume of cell suspension before buffer injection process for dividing the hanging droplet into two fractions). Therefore, the efficiencies corresponding to initial volumes were investigated in experimental study. We found that the initial volume should be optimized to find maximum separation efficiency.

Original language	English
Title of host publication	2006 5th IEEE Conference on Sensors
Pages	162-165
Number of pages	4
DOIs	https://doi.org/10.1109/ICSENS.2007.355744
Publication status	Published - 2006
Event	2006 5th IEEE Conference on Sensors - Daegu, Korea, Republic of Duration: 2006 Oct 22 → 2006 Oct 25

Publication series

Name	Proceedings of IEEE Sensors

Other

Other	2006 5th IEEE Conference on Sensors
Country/Territory	Korea, Republic of
City	Daegu
Period	06/10/22 → 06/10/25

ASJC Scopus subject areas

Electrical and Electronic Engineering

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10.1109/ICSENS.2007.355744

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Kim, Y, Hong, S, Lee, SH, Paek, K & Kim, B 2006, Droplet-based magnetically activated cell separator (DMACS): Evaluation of separation efficiency versus variance of magnetic flux density. in 2006 5th IEEE Conference on Sensors., 4178582, Proceedings of IEEE Sensors, pp. 162-165, 2006 5th IEEE Conference on Sensors, Daegu, Korea, Republic of, 06/10/22. https://doi.org/10.1109/ICSENS.2007.355744

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title = "Droplet-based magnetically activated cell separator (DMACS): Evaluation of separation efficiency versus variance of magnetic flux density",

abstract = "We introduced a droplet-based magnetically activated cell separator (DMACS) that utilizes a hanging droplet of microliter-sized volume for dividing positive (magnetically labeled) and negative (magnetically unlabeled) cells. It enabled us to solve adhesion problem in channel and showed better separation efficiency. However, the separation efficiency was changed under variations of initial volume (the droplet volume of cell suspension before buffer injection process for dividing the hanging droplet into two fractions). Therefore, the efficiencies corresponding to initial volumes were investigated in experimental study. We found that the initial volume should be optimized to find maximum separation efficiency.",

author = "Youngho Kim and Su Hong and Lee, {Sang Ho} and Kyeongkap Paek and Byungkyu Kim",

year = "2006",

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AB - We introduced a droplet-based magnetically activated cell separator (DMACS) that utilizes a hanging droplet of microliter-sized volume for dividing positive (magnetically labeled) and negative (magnetically unlabeled) cells. It enabled us to solve adhesion problem in channel and showed better separation efficiency. However, the separation efficiency was changed under variations of initial volume (the droplet volume of cell suspension before buffer injection process for dividing the hanging droplet into two fractions). Therefore, the efficiencies corresponding to initial volumes were investigated in experimental study. We found that the initial volume should be optimized to find maximum separation efficiency.

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BT - 2006 5th IEEE Conference on Sensors

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Droplet-based magnetically activated cell separator (DMACS): Evaluation of separation efficiency versus variance of magnetic flux density

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