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Keyphrases
Phase II Study
100%
Non-small Cell Lung Cancer (NSCLC)
100%
Locally Advanced Non-small Cell Lung Cancer (LA-NSCLC)
100%
Anaplastic Lymphoma Kinase
100%
Late Treatment
100%
Third-line Treatment
100%
Durvalumab
100%
Tumor Cells
77%
Objective Response
44%
Programmed Death-ligand 1 (PD-L1)
44%
Anti-PD-1
44%
PD-L1 Expression
33%
Tumor Expression
22%
Clinical Activity
22%
Treatment-related
22%
Serious Adverse Events
22%
Response Evaluation Criteria in Solid Tumors (RECIST)
22%
Infusion Reaction
22%
Pneumonitis
22%
Blinded Independent Central Review
22%
Non-small Cell Lung Cancer Cells
11%
Adverse Events
11%
Diarrhea
11%
Immune Response
11%
Asia
11%
Europe
11%
Gamma-glutamyltransferase
11%
Aspartate Aminotransferase
11%
Safety Profile
11%
North America
11%
Exclusion Criteria
11%
New Standards
11%
Disease Progression
11%
Platinum-based Chemotherapy
11%
Vomiting
11%
EGFR mutation
11%
Intravenous Infusion
11%
Clinical Benefit
11%
Activity Profile
11%
Treatment-related Adverse Events
11%
Clinical Safety
11%
Anaplastic Lymphoma Kinase Rearrangement
11%
Standard of Care
11%
Measurable Disease
11%
One Dose
11%
Genetic Aberrations
11%
Heavily Pretreated
11%
Lung Histology
11%
Retreatment
11%
Immune Checkpoint Inhibitors
11%
Past Exposure
11%
Accruals
11%
Single-arm Trial
11%
AstraZeneca
11%
Elevated Transaminases
11%
Tyrosine Kinase Inhibitor Therapy
11%
Anti-PD-L1 Antibody
11%
WHO Performance Status
11%
Immunotherapy Agents
11%
Immune-related Adverse Events
11%
Performance Status Score
11%
EGFR Tyrosine Kinase
11%
Standard Treatment Guidelines
11%
Medicine and Dentistry
Non Small Cell Lung Cancer
100%
Arm
100%
Durvalumab
100%
Epidermal Growth Factor Receptor
91%
Anaplastic Lymphoma Kinase
83%
Programmed Death-Ligand 1
83%
Tumor Cell
58%
Adverse Event
33%
Neoplasm
16%
Pneumonia
16%
Response Evaluation Criteria in Solid Tumors
16%
Infusion Related Reaction
16%
Small Cell Lung Cancer
8%
Disease
8%
Disease Exacerbation
8%
Aspartate Aminotransferase
8%
Immunity
8%
Intravenous Drug Administration
8%
Immunotherapy
8%
Protein Tyrosine Kinase
8%
Tyrosine-Kinase Inhibitor
8%
Diarrhea
8%
Gamma-Glutamyl Transpeptidase
8%
Retreatment
8%
Elevated Transaminases
8%
Immune Checkpoint Inhibitor
8%
Immune-Related Adverse Events
8%
Chemotherapy
8%
Pharmacology, Toxicology and Pharmaceutical Science
Non Small Cell Lung Cancer
100%
Durvalumab
100%
Epidermal Growth Factor Receptor
91%
Anaplastic Lymphoma Kinase
83%
Neoplasm
75%
Adverse Event
41%
Solid Malignant Neoplasm
16%
Pneumonia
16%
Infusion Related Reaction
16%
Diarrhea
8%
Disease
8%
Immunotherapy
8%
Aspartate Aminotransferase
8%
Gamma Glutamyltransferase
8%
Chemotherapy
8%
Small Cell Lung Cancer
8%
Disease Exacerbation
8%
Protein Tyrosine Kinase
8%
Protein Tyrosine Kinase Inhibitor
8%
Hypertransaminasemia
8%
Immune Checkpoint Inhibitor
8%
Biochemistry, Genetics and Molecular Biology
Epidermal Growth Factor Receptor
100%
Anaplastic Lymphoma Kinase
90%
PD-L1
90%
Immunity
18%
Receptor Tyrosine Kinase
9%
Tyrosine Kinase
9%
Aspartate Transaminase
9%
Gamma-Glutamyl Transpeptidase
9%
Genetics
9%
Tyrosine Kinase Inhibitor
9%
Immune Checkpoints
9%
Elevated Transaminases
9%