Abstract
Multi-atlas segmentation is a powerful approach to automated anatomy delineation via fusing label information from a set of spatially normalized atlases. For simplicity, many existing methods perform pairwise image registration, leading to inaccurate segmentation especially when shape variation is large. In this paper, we propose a dynamic tree-based strategy for effective large-deformation registration and multiatlas segmentation. To deal with local minima caused by large shape variation, coarse estimates of deformations are first obtained via alignment of automatically localized landmark points. A dynamic tree capturing the structural relationships between images is then used to further reduce misalignment errors. Validation on two real human brain datasets, ADNI and LPBA40, shows that our method significantly improves registration and segmentation accuracy.
Original language | English |
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Title of host publication | Medical Computer Vision |
Subtitle of host publication | Algorithms for Big Data - International Workshop, MCV 2015 and Held in Conjunction with MICCAI 2015, Revised Selected Papers |
Editors | Michael Kelm, Henning Müller, Bjoern Menze, Shaoting Zhang, Dimitris Metaxas, Georg Langs, Albert Montillo, Weidong Cai |
Publisher | Springer Verlag |
Pages | 137-145 |
Number of pages | 9 |
ISBN (Print) | 9783319420158 |
DOIs | |
Publication status | Published - 2016 |
Externally published | Yes |
Event | International Workshop on Medical Image Computing for Computer Assisted Intervention, 2015 MICCAI - Germany, Germany Duration: 2015 Oct 9 → 2015 Oct 9 |
Publication series
Name | Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) |
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Volume | 9601 LNCS |
ISSN (Print) | 0302-9743 |
ISSN (Electronic) | 1611-3349 |
Other
Other | International Workshop on Medical Image Computing for Computer Assisted Intervention, 2015 MICCAI |
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Country/Territory | Germany |
City | Germany |
Period | 15/10/9 → 15/10/9 |
Bibliographical note
Funding Information:This work was supported in part by a UNC BRIC-Radiology start-up fund, and NIH grants (EB006733, EB008374, EB009634, MH088520 and NIHM 5R01MH091645-02)
Publisher Copyright:
© Springer International Publishing Switzerland 2016.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
ASJC Scopus subject areas
- Theoretical Computer Science
- General Computer Science