Early Safety Monitoring of COVID-19 Vaccines in Healthcare Workers

Joon Young Song; Hee Jin Cheong; Sung Ran Kim; Sung Eun Lee; Su Hyun Kim; Ji Yun Noh; Young Kyung Yoon; Wonseok Choi; Dae Won Park; Jang Wook Sohn; Woo Joo Kim; Min Ja Kim

doi:10.3346/jkms.2021.36.e110

Early Safety Monitoring of COVID-19 Vaccines in Healthcare Workers

Joon Young Song, Hee Jin Cheong, Sung Ran Kim, Sung Eun Lee, Su Hyun Kim, Ji Yun Noh, Young Kyung Yoon, Wonseok Choi, Dae Won Park, Jang Wook Sohn, Woo Joo Kim, Min Ja Kim

Department of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

Hospital-based surveillance for adverse events was conducted on healthcare workers after they received the first dose of coronavirus disease 2019 (COVID-19) vaccine. Among the two new platform vaccines (messenger RNA- and adenoviral vector-based vaccines), the rates of systemic adverse events were significantly higher among adenovirus-vectored vaccine recipients. Fatigue (87.6% vs. 53.8%), myalgia (80.8% vs. 50.0%), headache (72.0% vs. 28.8%), and fever (≥ 38.0°C, 38.7% vs. 0%) were the most common adverse events among adenovirus-vectored vaccine recipients, but most symptoms resolved within 2 days. Both types of COVID-19 vaccines were generally safe, and serious adverse events rarely occurred.

Original language	English
Pages (from-to)	e110
Journal	Journal of Korean medical science
Volume	36
Issue number	15
DOIs	https://doi.org/10.3346/jkms.2021.36.e110
Publication status	Published - 2021 Apr 19

Keywords

Adverse Event
COVID-19
Safety
Surveillance
Vaccine

ASJC Scopus subject areas

Medicine(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.3346/jkms.2021.36.e110

Cite this

@article{bb02bfa1147a474aa0a46cd1c86095cc,

title = "Early Safety Monitoring of COVID-19 Vaccines in Healthcare Workers",

abstract = "Hospital-based surveillance for adverse events was conducted on healthcare workers after they received the first dose of coronavirus disease 2019 (COVID-19) vaccine. Among the two new platform vaccines (messenger RNA- and adenoviral vector-based vaccines), the rates of systemic adverse events were significantly higher among adenovirus-vectored vaccine recipients. Fatigue (87.6% vs. 53.8%), myalgia (80.8% vs. 50.0%), headache (72.0% vs. 28.8%), and fever (≥ 38.0°C, 38.7% vs. 0%) were the most common adverse events among adenovirus-vectored vaccine recipients, but most symptoms resolved within 2 days. Both types of COVID-19 vaccines were generally safe, and serious adverse events rarely occurred.",

keywords = "Adverse Event, COVID-19, Safety, Surveillance, Vaccine",

author = "Song, {Joon Young} and Cheong, {Hee Jin} and Kim, {Sung Ran} and Lee, {Sung Eun} and Kim, {Su Hyun} and Noh, {Ji Yun} and Yoon, {Young Kyung} and Wonseok Choi and Park, {Dae Won} and Sohn, {Jang Wook} and Kim, {Woo Joo} and Kim, {Min Ja}",

note = "Publisher Copyright: {\textcopyright} 2021 The Korean Academy of Medical Sciences.",

year = "2021",

month = apr,

day = "19",

doi = "10.3346/jkms.2021.36.e110",

language = "English",

volume = "36",

pages = "e110",

journal = "Journal of Korean Medical Science",

issn = "1011-8934",

publisher = "Korean Academy of Medical Science",

number = "15",

}

TY - JOUR

T1 - Early Safety Monitoring of COVID-19 Vaccines in Healthcare Workers

AU - Song, Joon Young

AU - Cheong, Hee Jin

AU - Kim, Sung Ran

AU - Lee, Sung Eun

AU - Kim, Su Hyun

AU - Noh, Ji Yun

AU - Yoon, Young Kyung

AU - Choi, Wonseok

AU - Park, Dae Won

AU - Sohn, Jang Wook

AU - Kim, Woo Joo

AU - Kim, Min Ja

PY - 2021/4/19

Y1 - 2021/4/19

N2 - Hospital-based surveillance for adverse events was conducted on healthcare workers after they received the first dose of coronavirus disease 2019 (COVID-19) vaccine. Among the two new platform vaccines (messenger RNA- and adenoviral vector-based vaccines), the rates of systemic adverse events were significantly higher among adenovirus-vectored vaccine recipients. Fatigue (87.6% vs. 53.8%), myalgia (80.8% vs. 50.0%), headache (72.0% vs. 28.8%), and fever (≥ 38.0°C, 38.7% vs. 0%) were the most common adverse events among adenovirus-vectored vaccine recipients, but most symptoms resolved within 2 days. Both types of COVID-19 vaccines were generally safe, and serious adverse events rarely occurred.

AB - Hospital-based surveillance for adverse events was conducted on healthcare workers after they received the first dose of coronavirus disease 2019 (COVID-19) vaccine. Among the two new platform vaccines (messenger RNA- and adenoviral vector-based vaccines), the rates of systemic adverse events were significantly higher among adenovirus-vectored vaccine recipients. Fatigue (87.6% vs. 53.8%), myalgia (80.8% vs. 50.0%), headache (72.0% vs. 28.8%), and fever (≥ 38.0°C, 38.7% vs. 0%) were the most common adverse events among adenovirus-vectored vaccine recipients, but most symptoms resolved within 2 days. Both types of COVID-19 vaccines were generally safe, and serious adverse events rarely occurred.

KW - Adverse Event

KW - COVID-19

KW - Safety

KW - Surveillance

KW - Vaccine

UR - http://www.scopus.com/inward/record.url?scp=85105040342&partnerID=8YFLogxK

U2 - 10.3346/jkms.2021.36.e110

DO - 10.3346/jkms.2021.36.e110

M3 - Article

C2 - 33876589

AN - SCOPUS:85105040342

SN - 1011-8934

VL - 36

SP - e110

JO - Journal of Korean Medical Science

JF - Journal of Korean Medical Science

IS - 15

ER -

Early Safety Monitoring of COVID-19 Vaccines in Healthcare Workers

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this