Abstract
The magnetic capture of mitochondrial VDAC2 with bacterial magnetic particles (BMPs) conjugated VDAC2 antibody (BMPs-Ab) significantly decreased the expressed intracellular calcium levels and neurotoxicity induced by Aβ. This magnetic modulation of mitochondrial VDAC, playing a key role in various Ca2+ flux pathways, should provide attractive targets for the future development of AD treatments.
Original language | English |
---|---|
Pages (from-to) | 63681-63684 |
Number of pages | 4 |
Journal | RSC Advances |
Volume | 4 |
Issue number | 109 |
DOIs | |
Publication status | Published - 2014 |
ASJC Scopus subject areas
- Chemistry(all)
- Chemical Engineering(all)