TY - JOUR
T1 - Effect of percutaneous transluminal angioplasty on tissue oxygenation in ischemic diabetic feet
AU - Kim, Hong Ryul
AU - Han, Seung Kyu
AU - Rha, Seung Woon
AU - Kim, Hyun Surk
AU - Kim, Woo Kyung
PY - 2011/1
Y1 - 2011/1
N2 - Percutaneous transluminal angioplasty (PTA) has been performed as an alternative to bypass surgery for improving tissue oxygenation in ischemic diabetic feet because the former is less invasive than the latter. The purpose of this study was to evaluate the effect of PTA on tissue oxygenation in ischemic diabetic feet. This study included 29 ischemic diabetic feet, as determined by a transcutaneous oxygen pressure (TcPO2)<30 mmHg. The PTA was carried out in 29 limbs. The PTA procedure was considered successful, acceptable, and failed when residual stenosis was<30%, between 30 and 50%, and>50%, respectively. For evaluation of tissue oxygenation, the foot TcPO2 was measured before PTA and weekly for 6 weeks after PTA. Immediately after PTA, 26 feet were evaluated as being successful and the remaining three as acceptable. Before PTA, the average foot TcPO2 was 12.7±8.9 mmHg. The TcPO2 values were increased to 43.6±24.1, 51.0±22.6, 58.3±23.0, 61.3±24.2, 59.0±22.2, and 53.8±21.0 mmHg 1, 2, 3, 4, 5, and 6 weeks after PTA, respectively (p<0.01). The PTA procedure significantly increases tissue oxygenation in ischemic diabetic feet. The maximal level of tissue oxygenation was measured on the fourth week following PTA.
AB - Percutaneous transluminal angioplasty (PTA) has been performed as an alternative to bypass surgery for improving tissue oxygenation in ischemic diabetic feet because the former is less invasive than the latter. The purpose of this study was to evaluate the effect of PTA on tissue oxygenation in ischemic diabetic feet. This study included 29 ischemic diabetic feet, as determined by a transcutaneous oxygen pressure (TcPO2)<30 mmHg. The PTA was carried out in 29 limbs. The PTA procedure was considered successful, acceptable, and failed when residual stenosis was<30%, between 30 and 50%, and>50%, respectively. For evaluation of tissue oxygenation, the foot TcPO2 was measured before PTA and weekly for 6 weeks after PTA. Immediately after PTA, 26 feet were evaluated as being successful and the remaining three as acceptable. Before PTA, the average foot TcPO2 was 12.7±8.9 mmHg. The TcPO2 values were increased to 43.6±24.1, 51.0±22.6, 58.3±23.0, 61.3±24.2, 59.0±22.2, and 53.8±21.0 mmHg 1, 2, 3, 4, 5, and 6 weeks after PTA, respectively (p<0.01). The PTA procedure significantly increases tissue oxygenation in ischemic diabetic feet. The maximal level of tissue oxygenation was measured on the fourth week following PTA.
UR - http://www.scopus.com/inward/record.url?scp=78751542918&partnerID=8YFLogxK
U2 - 10.1111/j.1524-475X.2010.00641.x
DO - 10.1111/j.1524-475X.2010.00641.x
M3 - Article
C2 - 21134031
AN - SCOPUS:78751542918
SN - 1067-1927
VL - 19
SP - 19
EP - 24
JO - Wound Repair and Regeneration
JF - Wound Repair and Regeneration
IS - 1
ER -
