Effect of scaffolds with bone growth factors on new bone formation

Hae Ryong Song; Swee Hin Teoh; Jun Ho Wang; Hak Jun Kim; Ji Hoon Bae; Sung Eun Kim; Jerry Chan; Zhi Yong Zhang; Chang Wug Oh

doi:10.4032/9789814267861

Effect of scaffolds with bone growth factors on new bone formation

Hae Ryong Song, Swee Hin Teoh, Jun Ho Wang, Hak Jun Kim, Ji Hoon Bae, Sung Eun Kim, Jerry Chan, Zhi Yong Zhang, Chang Wug Oh

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Bone tissue engineering (BTE) using scaffolds with growth factors/ stem cells has received some success in clinical trails. Recently, osteogenic scaffolds using absorbable or nonabsorbable biomaterials have being investigated to repair bone defects. Scaffolds can provide the osteoconduction effect as well as a media to trap cells and allow them to proliferate and differentiate. Bioreactors provide a means to uniformly coat the scaffolds with cells and allow cells to proliferate better. Here we describe our work on preclinical animal trials applying the above concept to regenerate bone.

Original language	English
Title of host publication	Handbook of Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine
Publisher	Pan Stanford Publishing Pte. Ltd.
Pages	871-901
Number of pages	31
ISBN (Print)	9789814267854
DOIs	https://doi.org/10.4032/9789814267861
Publication status	Published - 2012 Jan 31

ASJC Scopus subject areas

General Biochemistry,Genetics and Molecular Biology
General Medicine

Access to Document

10.4032/9789814267861

Cite this

@inbook{a1c231b6fd734efba30178f12ed1036b,

title = "Effect of scaffolds with bone growth factors on new bone formation",

abstract = "Bone tissue engineering (BTE) using scaffolds with growth factors/ stem cells has received some success in clinical trails. Recently, osteogenic scaffolds using absorbable or nonabsorbable biomaterials have being investigated to repair bone defects. Scaffolds can provide the osteoconduction effect as well as a media to trap cells and allow them to proliferate and differentiate. Bioreactors provide a means to uniformly coat the scaffolds with cells and allow cells to proliferate better. Here we describe our work on preclinical animal trials applying the above concept to regenerate bone.",

author = "Song, {Hae Ryong} and Teoh, {Swee Hin} and Wang, {Jun Ho} and Kim, {Hak Jun} and Bae, {Ji Hoon} and Kim, {Sung Eun} and Jerry Chan and Zhang, {Zhi Yong} and Oh, {Chang Wug}",

year = "2012",

month = jan,

day = "31",

doi = "10.4032/9789814267861",

language = "English",

isbn = "9789814267854",

pages = "871--901",

booktitle = "Handbook of Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine",

publisher = "Pan Stanford Publishing Pte. Ltd.",

}

TY - CHAP

T1 - Effect of scaffolds with bone growth factors on new bone formation

AU - Song, Hae Ryong

AU - Teoh, Swee Hin

AU - Wang, Jun Ho

AU - Kim, Hak Jun

AU - Bae, Ji Hoon

AU - Kim, Sung Eun

AU - Chan, Jerry

AU - Zhang, Zhi Yong

AU - Oh, Chang Wug

PY - 2012/1/31

Y1 - 2012/1/31

N2 - Bone tissue engineering (BTE) using scaffolds with growth factors/ stem cells has received some success in clinical trails. Recently, osteogenic scaffolds using absorbable or nonabsorbable biomaterials have being investigated to repair bone defects. Scaffolds can provide the osteoconduction effect as well as a media to trap cells and allow them to proliferate and differentiate. Bioreactors provide a means to uniformly coat the scaffolds with cells and allow cells to proliferate better. Here we describe our work on preclinical animal trials applying the above concept to regenerate bone.

AB - Bone tissue engineering (BTE) using scaffolds with growth factors/ stem cells has received some success in clinical trails. Recently, osteogenic scaffolds using absorbable or nonabsorbable biomaterials have being investigated to repair bone defects. Scaffolds can provide the osteoconduction effect as well as a media to trap cells and allow them to proliferate and differentiate. Bioreactors provide a means to uniformly coat the scaffolds with cells and allow cells to proliferate better. Here we describe our work on preclinical animal trials applying the above concept to regenerate bone.

UR - http://www.scopus.com/inward/record.url?scp=84881777757&partnerID=8YFLogxK

U2 - 10.4032/9789814267861

DO - 10.4032/9789814267861

M3 - Chapter

AN - SCOPUS:84881777757

SN - 9789814267854

SP - 871

EP - 901

BT - Handbook of Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine

PB - Pan Stanford Publishing Pte. Ltd.

ER -

Effect of scaffolds with bone growth factors on new bone formation

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this