Abstract
Poly (dimethylsiloxane) (PDMS) has become one of the popular materials in the field of bio-related microfluidic systems, and has been used for various biological assays. While the material is known to be biocompatible in general, it also has been reported that the attachment and survival rate of cells are limited on a PDMS substrate. In this paper, a simple and relevant method to improve the biocompatibility of PDMS is proposed; the effects of various treatments using ethanol, water, and boiling-water were evaluated. The results show that the boiling-water treatment is the most appropriate, time saving, and simple method to improve the biocompatibility of PDMS.
| Original language | English |
|---|---|
| Pages (from-to) | 39-43 |
| Number of pages | 5 |
| Journal | Biochip Journal |
| Volume | 2 |
| Issue number | 1 |
| Publication status | Published - 2008 |
Keywords
- Biocompatibility
- Fibroblast
- Microfluidic chip
- PDMS
ASJC Scopus subject areas
- Biotechnology
- Bioengineering
- Biomedical Engineering
- Electrical and Electronic Engineering