Effects of flow-rate ratio on startup and cyclic steady-state behaviors of simulated moving bed under linear conditions

Youn Sang Bae, Kyung Min Kim, Jong Ho Moon, Sang Hoon Byeon, Ik Sung Ahn, Chang Ha Lee

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


The influence of the flow-rate ratio (m-value) on the startup and the cyclic steady-state performance of the simulated moving bed (SMB) process were studied under the condition of a fixed feed flow rate. Each system was evaluated from the viewpoint of four performance parameters (major product concentration, purity, eluent consumption, and productivity). Flow-rate ratios of zones II and III (m2 and m3) played key roles in the startup and cyclic steady-state behaviors of the performance parameters compared to m-values of zones I and IV (m1 and m4) in the four-zone SMB process. However, the performance parameters were steeply changed near the operating boundaries of m1 and m4 even though their variation was smaller than the results from m2 and m3. In addition, the effects of m1 and m4 on the major product concentration were substantial in the operating range. The startup periods of both product concentrations were increased as the operating point in the triangle region became far from the diagonal in terms of m2 and m3. On the other hand, the variation of m1 and m4 could lead to a change in performance without any adjustment to the startup period.

Original languageEnglish
Pages (from-to)148-159
Number of pages12
JournalSeparation and Purification Technology
Issue number1
Publication statusPublished - 2008 Aug 1

Bibliographical note

Funding Information:
This work was supported by the Korea Energy Management Corporation (KEMC) and the Ministry of Commerce, Industry, and Energy (MOCIE).

Copyright 2008 Elsevier B.V., All rights reserved.


  • Cyclic steady-state behavior
  • Flow-rate ratio
  • Performance parameter
  • Simulated moving bed (SMB) chromatography
  • Startup

ASJC Scopus subject areas

  • Analytical Chemistry
  • Filtration and Separation


Dive into the research topics of 'Effects of flow-rate ratio on startup and cyclic steady-state behaviors of simulated moving bed under linear conditions'. Together they form a unique fingerprint.

Cite this