Efficiency of genomic DNA extraction dependent on the size of magnetic nanoclusters

Hyun Ah Cho; Ji Hyun Min; Jun Hua Wu; Jin Woo Jang; Chae Seung Lim; Young Keun Kim

doi:10.1063/1.4864736

Efficiency of genomic DNA extraction dependent on the size of magnetic nanoclusters

Hyun Ah Cho, Ji Hyun Min, Jun Hua Wu, Jin Woo Jang, Chae Seung Lim, Young Keun Kim

Research output: Contribution to journal › Article › peer-review

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Abstract

We report the efficiency of genomic DNA extraction as a function of particle size and quantity. For DNA extraction, we synthesized magnetic nanoclusters of various sizes and coated the surface of these magnetic nanoclusters with meso-2,3-dimercaptosuccinic acid. We showed that the nanoclusters had a tight particle size distribution and high crystallinity. Furthermore, we observed that the three types of magnetic nanoclusters studied exhibited ferrimagnetic behavior and that larger nanoclusters showed larger saturation magnetization values. The resultant efficiency of DNA extraction is inversely proportional to particle size in the range of nanoclusters tested, due to the fact that the surface-to-volume ratio decreases as particle size increases.

Original language	English
Article number	17B512
Journal	Journal of Applied Physics
Volume	115
Issue number	17
DOIs	https://doi.org/10.1063/1.4864736
Publication status	Published - 2014 May 7

ASJC Scopus subject areas

Physics and Astronomy(all)

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title = "Efficiency of genomic DNA extraction dependent on the size of magnetic nanoclusters",

abstract = "We report the efficiency of genomic DNA extraction as a function of particle size and quantity. For DNA extraction, we synthesized magnetic nanoclusters of various sizes and coated the surface of these magnetic nanoclusters with meso-2,3-dimercaptosuccinic acid. We showed that the nanoclusters had a tight particle size distribution and high crystallinity. Furthermore, we observed that the three types of magnetic nanoclusters studied exhibited ferrimagnetic behavior and that larger nanoclusters showed larger saturation magnetization values. The resultant efficiency of DNA extraction is inversely proportional to particle size in the range of nanoclusters tested, due to the fact that the surface-to-volume ratio decreases as particle size increases.",

author = "Cho, {Hyun Ah} and {Hyun Min}, Ji and {Hua Wu}, Jun and {Woo Jang}, Jin and Lim, {Chae Seung} and {Keun Kim}, Young",

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AU - Cho, Hyun Ah

AU - Hyun Min, Ji

AU - Hua Wu, Jun

AU - Woo Jang, Jin

AU - Lim, Chae Seung

AU - Keun Kim, Young

PY - 2014/5/7

Y1 - 2014/5/7

N2 - We report the efficiency of genomic DNA extraction as a function of particle size and quantity. For DNA extraction, we synthesized magnetic nanoclusters of various sizes and coated the surface of these magnetic nanoclusters with meso-2,3-dimercaptosuccinic acid. We showed that the nanoclusters had a tight particle size distribution and high crystallinity. Furthermore, we observed that the three types of magnetic nanoclusters studied exhibited ferrimagnetic behavior and that larger nanoclusters showed larger saturation magnetization values. The resultant efficiency of DNA extraction is inversely proportional to particle size in the range of nanoclusters tested, due to the fact that the surface-to-volume ratio decreases as particle size increases.

AB - We report the efficiency of genomic DNA extraction as a function of particle size and quantity. For DNA extraction, we synthesized magnetic nanoclusters of various sizes and coated the surface of these magnetic nanoclusters with meso-2,3-dimercaptosuccinic acid. We showed that the nanoclusters had a tight particle size distribution and high crystallinity. Furthermore, we observed that the three types of magnetic nanoclusters studied exhibited ferrimagnetic behavior and that larger nanoclusters showed larger saturation magnetization values. The resultant efficiency of DNA extraction is inversely proportional to particle size in the range of nanoclusters tested, due to the fact that the surface-to-volume ratio decreases as particle size increases.

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VL - 115

JO - Journal of Applied Physics

JF - Journal of Applied Physics

IS - 17

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ER -

Efficiency of genomic DNA extraction dependent on the size of magnetic nanoclusters

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