Electrochemical detection of DNA mutations on a PNA-modified electrode utilizing a single-stranded DNA specific endonuclease

Sujeong Shin; Byoung Yeon Won; Cheulhee Jung; Sung Chul Shin; Dae Yeon Cho; Soo Suk Lee; Hyun Gyu Park

doi:10.1039/c1cc11476j

Electrochemical detection of DNA mutations on a PNA-modified electrode utilizing a single-stranded DNA specific endonuclease

Sujeong Shin, Byoung Yeon Won, Cheulhee Jung, Sung Chul Shin, Dae Yeon Cho, Soo Suk Lee, Hyun Gyu Park

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

Utilizing a peptide nucleic acid (PNA)-modified electrode and a single-stranded DNA specific endonuclease, a novel electrochemical method to identify DNA mutations has been developed and represents a totally new strategy for the electrochemical diagnosis of human genetic mutations.

Original language	English
Pages (from-to)	6611-6613
Number of pages	3
Journal	Chemical Communications
Volume	47
Issue number	23
DOIs	https://doi.org/10.1039/c1cc11476j
Publication status	Published - 2011 Jun 21
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c1cc11476j

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title = "Electrochemical detection of DNA mutations on a PNA-modified electrode utilizing a single-stranded DNA specific endonuclease",

abstract = "Utilizing a peptide nucleic acid (PNA)-modified electrode and a single-stranded DNA specific endonuclease, a novel electrochemical method to identify DNA mutations has been developed and represents a totally new strategy for the electrochemical diagnosis of human genetic mutations.",

author = "Sujeong Shin and Won, {Byoung Yeon} and Cheulhee Jung and Shin, {Sung Chul} and Cho, {Dae Yeon} and Lee, {Soo Suk} and Park, {Hyun Gyu}",

year = "2011",

month = jun,

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doi = "10.1039/c1cc11476j",

language = "English",

volume = "47",

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journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

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T1 - Electrochemical detection of DNA mutations on a PNA-modified electrode utilizing a single-stranded DNA specific endonuclease

AU - Shin, Sujeong

AU - Won, Byoung Yeon

AU - Jung, Cheulhee

AU - Shin, Sung Chul

AU - Cho, Dae Yeon

AU - Lee, Soo Suk

AU - Park, Hyun Gyu

PY - 2011/6/21

Y1 - 2011/6/21

N2 - Utilizing a peptide nucleic acid (PNA)-modified electrode and a single-stranded DNA specific endonuclease, a novel electrochemical method to identify DNA mutations has been developed and represents a totally new strategy for the electrochemical diagnosis of human genetic mutations.

AB - Utilizing a peptide nucleic acid (PNA)-modified electrode and a single-stranded DNA specific endonuclease, a novel electrochemical method to identify DNA mutations has been developed and represents a totally new strategy for the electrochemical diagnosis of human genetic mutations.

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U2 - 10.1039/c1cc11476j

DO - 10.1039/c1cc11476j

M3 - Article

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AN - SCOPUS:79957974424

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JO - Chemical Communications

JF - Chemical Communications

IS - 23

ER -

Electrochemical detection of DNA mutations on a PNA-modified electrode utilizing a single-stranded DNA specific endonuclease

Abstract

ASJC Scopus subject areas

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