Electromagnetic low-intensity extracorporeal shock wave therapy in patients with erectile dysfunction: A sham-controlled, double-blind, randomized prospective study

Kang Sup Kim, Hyun Cheol Jeong, Sae Woong Choi, Yong Sun Choi, Hyuk Jin Cho, U. Syn Ha, Sung Hoo Hong, Ji Youl Lee, Seung Wook Lee, Sun Tae Ahn, Du Geon Moon, Woong Jin Bae, Sae Woong Kim

    Research output: Contribution to journalReview articlepeer-review

    20 Citations (Scopus)

    Abstract

    Purpose: The aim of the present study was to evaluate the efficacy and safety of the electromagnetic-type low-intensity extracorporeal shock wave therapy (Li-ESWT) in patients with erectile dysfunction (ED). Materials and Methods: The randomized, sham-controlled, double-blind prospective study was performed at two referral hospitals. Participants were randomized in a 1:1 ratio to receive sham or Li-ESWT for 6 weeks. ED was evaluated at screening and at 4 and 7 weeks after treatment. Participants were asked to complete the international index of erectile function-erectile function (IIEF-EF) domain questionnaire, erection hardness scale (EHS), and sexual encounter profile questionnaire (SEPQ 2 and 3). The development of complications was investigated. Results: Eighty-one of 96 patients completed the study. The median change in the IIEF-EF score in the Li-ESWT and sham groups was 5.1 and -2.2 (p<0.001), respectively, at the 7-week follow-up; 47.4% (18/38) patients had EHS <3, of which 77.8% (14/18) showed significant improvement in virtue of Li-ESWT treatment (p=0.001). A significant improvement was observed in the percentage of ‘Yes” responses to SEPQ 2 and 3 in the Li-ESWT group vs. sham group from baseline to 7-week follow-up (91.3% vs. 69.4%; p=0.008 and 50.0% vs. 14.3%; p=0.002, respectively). No patients reported pain or other adverse events during treatment or follow-up. Conclusions: Thus, Li-ESWT could have a role in improving erectile function. Furthermore, it is safe. We believe that Li-ESWT is an attractive new treatment modality for patients with ED.

    Original languageEnglish
    Pages (from-to)236-242
    Number of pages7
    JournalWorld Journal of Men?s Health
    Volume38
    Issue number2
    DOIs
    Publication statusPublished - 2020 Apr

    Bibliographical note

    Funding Information:
    This research was supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), fund-

    Funding Information:
    This research was supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Korea (grant HI17C1944).

    Publisher Copyright:
    Copyright © 2020 Korean Society for Sexual Medicine and Andrology.

    Keywords

    • Electromagnetic
    • Erectile dysfunction
    • Humans
    • Low-intensity extracorporeal shock wave therapy

    ASJC Scopus subject areas

    • Public Health, Environmental and Occupational Health
    • Psychiatry and Mental health
    • Urology
    • Pharmacology (medical)
    • Ageing
    • Health Policy
    • Reproductive Medicine

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