EMR for early gastric cancer in Korea: a multicenter retrospective study

Jae J. Kim; Jun Haeng Lee; Hwoon Yong Jung; Gin Hyug Lee; Joo Yong Cho; Chang Beom Ryu; Hoon Jai Chun; Jong Jae Park; Wan Sik Lee; Hyun Soo Kim; Moon Gi Chung; Jeong Seop Moon; Seok Reyol Choi; Geun Am Song; Hyun Yong Jeong; Sam Ryong Jee; Sang Yong Seol; Yong Bum Yoon

doi:10.1016/j.gie.2007.04.013

EMR for early gastric cancer in Korea: a multicenter retrospective study

Jae J. Kim, Jun Haeng Lee, Hwoon Yong Jung, Gin Hyug Lee, Joo Yong Cho, Chang Beom Ryu, Hoon Jai Chun, Jong Jae Park, Wan Sik Lee, Hyun Soo Kim, Moon Gi Chung, Jeong Seop Moon, Seok Reyol Choi, Geun Am Song, Hyun Yong Jeong, Sam Ryong Jee, Sang Yong Seol, Yong Bum Yoon

Research output: Contribution to journal › Article › peer-review

106 Citations (Scopus)

Abstract

Background: EMR has been accepted as a treatment modality for selected cases of early gastric cancer (EGC) in Japan. However, long-term outcomes after EMR for EGC have not been fully documented. Objectives: We reviewed the experiences of EMR for EGC in Korea, with emphasis on the long-term outcome. Design: Multicenter, retrospective study. Methods: Data were collected retrospectively by use of the on-line database registry system. From January 2000 to December 2002, 514 EGCs in 506 patients were treated by EMR in 13 institutions in Korea. Median age of the patients was 60 years (range 45-83 years). The resection was regarded as incomplete if histopathologic examination revealed a positive resection margin or submucosal invasion or positive lymphovascular invasion or undifferentiated histologic diagnosis. Results: The most commonly used technique was circumferential precutting followed by snare resection (EMR-P, n = 269, 52.3%). Complete resection and incomplete resection after EMR were confirmed in 399 lesions (77.6%) and 103 lesions (20.0%), respectively. For completely resected mucosal cancers (n = 399), the median duration of follow-up was 23.5 months (range 5-70 months). In this group, local recurrence was detected in 24 cases (6.0%) with a median interval between EMR and recurrence of 17.9 months (range 3.5-51.7 months). There were 3 cases with perforation and 71 cases with bleeding. No deaths were related to recurrence of gastric cancer during the overall median follow-up period of 39 months. Limitations: Multicenter retrospective design, no controls. Conclusions: EMR is an effective therapeutic modality for selected cases of EGC in Korea.

Original language	English
Pages (from-to)	693-700
Number of pages	8
Journal	Gastrointestinal Endoscopy
Volume	66
Issue number	4
DOIs	https://doi.org/10.1016/j.gie.2007.04.013
Publication status	Published - 2007 Oct
Externally published	Yes

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Gastroenterology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.gie.2007.04.013

Cite this

Kim, J. J., Lee, J. H., Jung, H. Y., Lee, G. H., Cho, J. Y., Ryu, C. B., Chun, H. J., Park, J. J., Lee, W. S., Kim, H. S., Chung, M. G., Moon, J. S., Choi, S. R., Song, G. A., Jeong, H. Y., Jee, S. R., Seol, S. Y., & Yoon, Y. B. (2007). EMR for early gastric cancer in Korea: a multicenter retrospective study. Gastrointestinal Endoscopy, 66(4), 693-700. https://doi.org/10.1016/j.gie.2007.04.013

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title = "EMR for early gastric cancer in Korea: a multicenter retrospective study",

abstract = "Background: EMR has been accepted as a treatment modality for selected cases of early gastric cancer (EGC) in Japan. However, long-term outcomes after EMR for EGC have not been fully documented. Objectives: We reviewed the experiences of EMR for EGC in Korea, with emphasis on the long-term outcome. Design: Multicenter, retrospective study. Methods: Data were collected retrospectively by use of the on-line database registry system. From January 2000 to December 2002, 514 EGCs in 506 patients were treated by EMR in 13 institutions in Korea. Median age of the patients was 60 years (range 45-83 years). The resection was regarded as incomplete if histopathologic examination revealed a positive resection margin or submucosal invasion or positive lymphovascular invasion or undifferentiated histologic diagnosis. Results: The most commonly used technique was circumferential precutting followed by snare resection (EMR-P, n = 269, 52.3%). Complete resection and incomplete resection after EMR were confirmed in 399 lesions (77.6%) and 103 lesions (20.0%), respectively. For completely resected mucosal cancers (n = 399), the median duration of follow-up was 23.5 months (range 5-70 months). In this group, local recurrence was detected in 24 cases (6.0%) with a median interval between EMR and recurrence of 17.9 months (range 3.5-51.7 months). There were 3 cases with perforation and 71 cases with bleeding. No deaths were related to recurrence of gastric cancer during the overall median follow-up period of 39 months. Limitations: Multicenter retrospective design, no controls. Conclusions: EMR is an effective therapeutic modality for selected cases of EGC in Korea.",

author = "Kim, {Jae J.} and Lee, {Jun Haeng} and Jung, {Hwoon Yong} and Lee, {Gin Hyug} and Cho, {Joo Yong} and Ryu, {Chang Beom} and Chun, {Hoon Jai} and Park, {Jong Jae} and Lee, {Wan Sik} and Kim, {Hyun Soo} and Chung, {Moon Gi} and Moon, {Jeong Seop} and Choi, {Seok Reyol} and Song, {Geun Am} and Jeong, {Hyun Yong} and Jee, {Sam Ryong} and Seol, {Sang Yong} and Yoon, {Yong Bum}",

year = "2007",

month = oct,

doi = "10.1016/j.gie.2007.04.013",

language = "English",

volume = "66",

pages = "693--700",

journal = "Gastrointestinal Endoscopy",

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TY - JOUR

T1 - EMR for early gastric cancer in Korea

T2 - a multicenter retrospective study

AU - Kim, Jae J.

AU - Lee, Jun Haeng

AU - Jung, Hwoon Yong

AU - Lee, Gin Hyug

AU - Cho, Joo Yong

AU - Ryu, Chang Beom

AU - Chun, Hoon Jai

AU - Park, Jong Jae

AU - Lee, Wan Sik

AU - Kim, Hyun Soo

AU - Chung, Moon Gi

AU - Moon, Jeong Seop

AU - Choi, Seok Reyol

AU - Song, Geun Am

AU - Jeong, Hyun Yong

AU - Jee, Sam Ryong

AU - Seol, Sang Yong

AU - Yoon, Yong Bum

PY - 2007/10

Y1 - 2007/10

N2 - Background: EMR has been accepted as a treatment modality for selected cases of early gastric cancer (EGC) in Japan. However, long-term outcomes after EMR for EGC have not been fully documented. Objectives: We reviewed the experiences of EMR for EGC in Korea, with emphasis on the long-term outcome. Design: Multicenter, retrospective study. Methods: Data were collected retrospectively by use of the on-line database registry system. From January 2000 to December 2002, 514 EGCs in 506 patients were treated by EMR in 13 institutions in Korea. Median age of the patients was 60 years (range 45-83 years). The resection was regarded as incomplete if histopathologic examination revealed a positive resection margin or submucosal invasion or positive lymphovascular invasion or undifferentiated histologic diagnosis. Results: The most commonly used technique was circumferential precutting followed by snare resection (EMR-P, n = 269, 52.3%). Complete resection and incomplete resection after EMR were confirmed in 399 lesions (77.6%) and 103 lesions (20.0%), respectively. For completely resected mucosal cancers (n = 399), the median duration of follow-up was 23.5 months (range 5-70 months). In this group, local recurrence was detected in 24 cases (6.0%) with a median interval between EMR and recurrence of 17.9 months (range 3.5-51.7 months). There were 3 cases with perforation and 71 cases with bleeding. No deaths were related to recurrence of gastric cancer during the overall median follow-up period of 39 months. Limitations: Multicenter retrospective design, no controls. Conclusions: EMR is an effective therapeutic modality for selected cases of EGC in Korea.

AB - Background: EMR has been accepted as a treatment modality for selected cases of early gastric cancer (EGC) in Japan. However, long-term outcomes after EMR for EGC have not been fully documented. Objectives: We reviewed the experiences of EMR for EGC in Korea, with emphasis on the long-term outcome. Design: Multicenter, retrospective study. Methods: Data were collected retrospectively by use of the on-line database registry system. From January 2000 to December 2002, 514 EGCs in 506 patients were treated by EMR in 13 institutions in Korea. Median age of the patients was 60 years (range 45-83 years). The resection was regarded as incomplete if histopathologic examination revealed a positive resection margin or submucosal invasion or positive lymphovascular invasion or undifferentiated histologic diagnosis. Results: The most commonly used technique was circumferential precutting followed by snare resection (EMR-P, n = 269, 52.3%). Complete resection and incomplete resection after EMR were confirmed in 399 lesions (77.6%) and 103 lesions (20.0%), respectively. For completely resected mucosal cancers (n = 399), the median duration of follow-up was 23.5 months (range 5-70 months). In this group, local recurrence was detected in 24 cases (6.0%) with a median interval between EMR and recurrence of 17.9 months (range 3.5-51.7 months). There were 3 cases with perforation and 71 cases with bleeding. No deaths were related to recurrence of gastric cancer during the overall median follow-up period of 39 months. Limitations: Multicenter retrospective design, no controls. Conclusions: EMR is an effective therapeutic modality for selected cases of EGC in Korea.

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DO - 10.1016/j.gie.2007.04.013

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SN - 0016-5107

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JO - Gastrointestinal Endoscopy

JF - Gastrointestinal Endoscopy

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