Enantioselective syntheses of decursinol angelate and decursin

Jongdoo Lim, Ik Hwan Kim, Hyeon Ho Kim, Kyung Seop Ahn, Hogyu Han

Research output: Contribution to journalArticlepeer-review

33 Citations (Scopus)

Abstract

The practical enantioselective syntheses of decursinol angelate and decursin were achieved in eight steps from resorcinol. The stereochemistry was addressed using the catalytic asymmetric epoxidation of 7-acetoxy-2,2-dimethylchromene by chiral (salen)Mn complexes as the key step.

Original languageEnglish
Pages (from-to)4001-4003
Number of pages3
JournalTetrahedron Letters
Volume42
Issue number24
DOIs
Publication statusPublished - 2001 Jun 11

Keywords

  • Catalytic asymmetric epoxidation
  • Decursin
  • Decursinol
  • Decursinol angelate
  • Protein kinase C

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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