@inproceedings{1cc8ca8df1e248308ea804f1699c6590,
title = "Enhanced cell labeling with electropreconcentration",
abstract = "This study presents a high efficiency on-chip tumor cell labeling technique for cell-based diagnostics by taking advantage from local enhancement of antibody's concentration. Two different approaches, namely overlapping EDL in nanochannels and negatively charged polymer, have been applied for utilizing ion-selectivity in order to induce preconcentration. It has been found that electro-kinetic insatiability in ion concentration polarization results in microcirculation, which facilitates labeling as a result of larger convective terms. Experiments showed that owing to both locally-increased concentration of antibody and microcirculations required time for labeling dramatically decreased to two minutes compared to 45 minute-long conventional labeling procedure.",
keywords = "Cell labeling, Ion selectivity, Preconcentration",
author = "H. Shirinkami and B. Kim and H. Chun",
note = "Publisher Copyright: {\textcopyright} 15CBMS-0001.; 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 ; Conference date: 25-10-2015 Through 29-10-2015",
year = "2015",
language = "English",
series = "MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
publisher = "Chemical and Biological Microsystems Society",
pages = "987--989",
booktitle = "MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
}