Enzymatic 'charging' of synthetic polymers

Jingyi Rao, Anzar Khan

    Research output: Contribution to journalArticlepeer-review

    26 Citations (Scopus)

    Abstract

    Actuated by an enzyme, a purely synthetic and chemically neutral polymer chain transforms into a chemically charged cationic structure. This biologically triggered structural change enables the polymer chain to recognize a negatively charged biomolecule (RNA) through electrostatic interactions in aqueous environment. The supramolecular recognition event ultimately leads to the assembly of oppositely charged, artificial and natural polymer chains, into the polyion complex-based nanoparticles.

    Original languageEnglish
    Pages (from-to)686-690
    Number of pages5
    JournalPolymer Chemistry
    Volume6
    Issue number5
    DOIs
    Publication statusPublished - 2015 Feb 7

    ASJC Scopus subject areas

    • Bioengineering
    • Biochemistry
    • Polymers and Plastics
    • Organic Chemistry

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