Enzyme-free glucose sensors with channels composed of necked ZnO nanoparticles on plastic

Sukhyung Park; Kyoungah Cho; Sangsig Kim

doi:10.1016/j.mee.2011.02.054

Enzyme-free glucose sensors with channels composed of necked ZnO nanoparticles on plastic

Sukhyung Park, Kyoungah Cho, Sangsig Kim

School of Electrical Engineering

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

In this study, enzyme-free glucose sensors with channels composed of necked zinc oxide (ZnO) nanoparticles (NPs) are constructed on a plastic substrate, and their sensing characteristics are examined. When a phosphate buffer solution (PBS) of lower pH than the isoelectric point of ZnO is adsorbed on the necked ZnO NP channels, the current increases remarkably in magnitude at a bias voltage of 10 V compared with ZnO NP channels without the adsorption of PBS. The current decreases in magnitude with increasing number of moles of added glucose. When 2.5 × 10^-12 moles of glucose are adsorbed on the PBS-adsorbed channels, the current in the channels at 10 V decreases in magnitude from 4.7 μA to 600 nA. The enzyme-free glucose sensors can detect 5 × 10^-13 moles of glucose in air at room temperature.

Original language	English
Pages (from-to)	2611-2613
Number of pages	3
Journal	Microelectronic Engineering
Volume	88
Issue number	8
DOIs	https://doi.org/10.1016/j.mee.2011.02.054
Publication status	Published - 2011 Aug

Keywords

Biosensor
Enzyme-free
Glucose
Plastic sensor

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Condensed Matter Physics
Surfaces, Coatings and Films
Electrical and Electronic Engineering

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10.1016/j.mee.2011.02.054

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title = "Enzyme-free glucose sensors with channels composed of necked ZnO nanoparticles on plastic",

abstract = "In this study, enzyme-free glucose sensors with channels composed of necked zinc oxide (ZnO) nanoparticles (NPs) are constructed on a plastic substrate, and their sensing characteristics are examined. When a phosphate buffer solution (PBS) of lower pH than the isoelectric point of ZnO is adsorbed on the necked ZnO NP channels, the current increases remarkably in magnitude at a bias voltage of 10 V compared with ZnO NP channels without the adsorption of PBS. The current decreases in magnitude with increasing number of moles of added glucose. When 2.5 × 10-12 moles of glucose are adsorbed on the PBS-adsorbed channels, the current in the channels at 10 V decreases in magnitude from 4.7 μA to 600 nA. The enzyme-free glucose sensors can detect 5 × 10-13 moles of glucose in air at room temperature.",

keywords = "Biosensor, Enzyme-free, Glucose, Plastic sensor",

author = "Sukhyung Park and Kyoungah Cho and Sangsig Kim",

note = "Funding Information: This work was supported by the IT R&D program of MKE/KEIT (10030559, Development of next-generation high-performance organic/nano materials and printing process technology), the Nano R&D Program (M10703000980-08M0300-98010), and the World Class University Project (WCU, R32-2008-000-10082-0) of the Ministry of Education, Science, and Technology (Korea Science and Engineering Foundation). ",

year = "2011",

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doi = "10.1016/j.mee.2011.02.054",

language = "English",

volume = "88",

pages = "2611--2613",

journal = "Microelectronic Engineering",

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AU - Park, Sukhyung

AU - Cho, Kyoungah

AU - Kim, Sangsig

N1 - Funding Information: This work was supported by the IT R&D program of MKE/KEIT (10030559, Development of next-generation high-performance organic/nano materials and printing process technology), the Nano R&D Program (M10703000980-08M0300-98010), and the World Class University Project (WCU, R32-2008-000-10082-0) of the Ministry of Education, Science, and Technology (Korea Science and Engineering Foundation).

PY - 2011/8

Y1 - 2011/8

N2 - In this study, enzyme-free glucose sensors with channels composed of necked zinc oxide (ZnO) nanoparticles (NPs) are constructed on a plastic substrate, and their sensing characteristics are examined. When a phosphate buffer solution (PBS) of lower pH than the isoelectric point of ZnO is adsorbed on the necked ZnO NP channels, the current increases remarkably in magnitude at a bias voltage of 10 V compared with ZnO NP channels without the adsorption of PBS. The current decreases in magnitude with increasing number of moles of added glucose. When 2.5 × 10-12 moles of glucose are adsorbed on the PBS-adsorbed channels, the current in the channels at 10 V decreases in magnitude from 4.7 μA to 600 nA. The enzyme-free glucose sensors can detect 5 × 10-13 moles of glucose in air at room temperature.

AB - In this study, enzyme-free glucose sensors with channels composed of necked zinc oxide (ZnO) nanoparticles (NPs) are constructed on a plastic substrate, and their sensing characteristics are examined. When a phosphate buffer solution (PBS) of lower pH than the isoelectric point of ZnO is adsorbed on the necked ZnO NP channels, the current increases remarkably in magnitude at a bias voltage of 10 V compared with ZnO NP channels without the adsorption of PBS. The current decreases in magnitude with increasing number of moles of added glucose. When 2.5 × 10-12 moles of glucose are adsorbed on the PBS-adsorbed channels, the current in the channels at 10 V decreases in magnitude from 4.7 μA to 600 nA. The enzyme-free glucose sensors can detect 5 × 10-13 moles of glucose in air at room temperature.

KW - Biosensor

KW - Enzyme-free

KW - Glucose

KW - Plastic sensor

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DO - 10.1016/j.mee.2011.02.054

M3 - Article

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SN - 0167-9317

VL - 88

SP - 2611

EP - 2613

JO - Microelectronic Engineering

JF - Microelectronic Engineering

IS - 8

ER -

Enzyme-free glucose sensors with channels composed of necked ZnO nanoparticles on plastic

Abstract

Keywords

ASJC Scopus subject areas

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