Estimation of the secondary cancer risk induced by diagnostic imaging radiation during proton therapy

Hojin Jeong, Jeong Eun Rah, Ui Jung Hwang, Seung Hoon Yoo, Byung Jun Min, Sang Yeob Lee, Myonggeun Yoon, Dong Ho Shin, Sung Yong Park, Se Byeong Lee, Joo Young Kim

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


We have estimated the secondary cancer risk (SCR) introduced by image-guided procedures during proton therapy. The physical dose from imaging radiation and the corresponding organ equivalent dose were calculated for the case of a lumbar spine patient. The maximum physical dose delivered to the patient during the imaging procedure was estimated to be ∼ 0.35% of the prescribed dose of 46Gy. However, this small imaging dose substantially raised the radiation-induced SCR by ∼ 8%. In addition, the clinical benefit (improved accuracy during the procedure) and costs (extra SCR) associated with image-guided procedures were quantitatively modelled by systematically investigating the changes in SCR as a function of the prescribed dose, treatment target volume and imaging field size. The results showed that the SCR varied sensitively with the volume receiving the imaging and the therapeutic radiation, whereas the SCR depended to a lesser extent on the magnitude of the applied therapeutic radiation. These results showed that the additional SCR introduced by imaging radiation could be efficiently reduced by minimizing the imaging field size during image-guided procedures.

Original languageEnglish
Pages (from-to)477-487
Number of pages11
JournalJournal of Radiological Protection
Issue number4
Publication statusPublished - 2011 Dec
Externally publishedYes

ASJC Scopus subject areas

  • Waste Management and Disposal
  • Public Health, Environmental and Occupational Health


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