Evaluation of rapid immunocapture assays for diagnosis of Plasmodium vivax in Korea

Duck Cho, Kwang Hee Kim, Seung Chul Park, Young Kee Kim, Kap No Lee, Chae Seung Lim

Research output: Contribution to journalArticlepeer-review

32 Citations (Scopus)

Abstract

The rapid immunocapture assays, OptiMal and ICT, were evaluated from 87 individuals for the diagnosis of malaria infections directly from whole blood. A total of 87 individuals was examined for malaria parasites by microscopic examination of Giemsastained blood smears, and 65 cases were positive for Plasmodium vivax by microscopy. Correspondingly, the OptiMal test identified malaria infection in 45 cases (69.2%) of microscopy positive cases. Of these, two cases were misinterpreted as Plasmodium falciparum, whereas ICT detected P. vivax infection in 29 (44.6%) patients. We would like to propose that rapid immuno capture assays are an easy method that can serve as a useful tool in addition to microscopy for the diagnosis of malaria, but sensitivity is not yet satisfactory for diagnosis of P. vivax in Korea.

Original languageEnglish
Pages (from-to)445-448
Number of pages4
JournalParasitology Research
Volume87
Issue number6
DOIs
Publication statusPublished - 2001

Bibliographical note

Funding Information:
Acknowledgements We most gratefully acknowledge the financial support granted by the Medical Science Research Center of Korea University and the grant from the Ministry of Health and Welfare, Republic of Korea (Grant No HMP-99-M-04–0002).

Keywords

  • ICT
  • Immunocapture assay
  • OptiMal
  • Plasmodium vivax
  • South Korea

ASJC Scopus subject areas

  • Parasitology
  • veterinary(all)
  • Insect Science
  • Infectious Diseases

Fingerprint

Dive into the research topics of 'Evaluation of rapid immunocapture assays for diagnosis of Plasmodium vivax in Korea'. Together they form a unique fingerprint.

Cite this