Evaluation of rapid immunocapture assays for diagnosis of Plasmodium vivax in Korea

Duck Cho; Kwang Hee Kim; Seung Chul Park; Young Kee Kim; Kap No Lee; Chae Seung Lim

doi:10.1007/s004360000360

Evaluation of rapid immunocapture assays for diagnosis of Plasmodium vivax in Korea

Duck Cho, Kwang Hee Kim, Seung Chul Park, Young Kee Kim, Kap No Lee, Chae Seung Lim

Research output: Contribution to journal › Article › peer-review

32 Citations (Scopus)

Abstract

The rapid immunocapture assays, OptiMal and ICT, were evaluated from 87 individuals for the diagnosis of malaria infections directly from whole blood. A total of 87 individuals was examined for malaria parasites by microscopic examination of Giemsastained blood smears, and 65 cases were positive for Plasmodium vivax by microscopy. Correspondingly, the OptiMal test identified malaria infection in 45 cases (69.2%) of microscopy positive cases. Of these, two cases were misinterpreted as Plasmodium falciparum, whereas ICT detected P. vivax infection in 29 (44.6%) patients. We would like to propose that rapid immuno capture assays are an easy method that can serve as a useful tool in addition to microscopy for the diagnosis of malaria, but sensitivity is not yet satisfactory for diagnosis of P. vivax in Korea.

Original language	English
Pages (from-to)	445-448
Number of pages	4
Journal	Parasitology Research
Volume	87
Issue number	6
DOIs	https://doi.org/10.1007/s004360000360
Publication status	Published - 2001

Bibliographical note

Funding Information:
Acknowledgements We most gratefully acknowledge the financial support granted by the Medical Science Research Center of Korea University and the grant from the Ministry of Health and Welfare, Republic of Korea (Grant No HMP-99-M-04–0002).

Keywords

ICT
Immunocapture assay
OptiMal
Plasmodium vivax
South Korea

ASJC Scopus subject areas

Parasitology
veterinary(all)
Insect Science
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s004360000360

Cite this

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title = "Evaluation of rapid immunocapture assays for diagnosis of Plasmodium vivax in Korea",

abstract = "The rapid immunocapture assays, OptiMal and ICT, were evaluated from 87 individuals for the diagnosis of malaria infections directly from whole blood. A total of 87 individuals was examined for malaria parasites by microscopic examination of Giemsastained blood smears, and 65 cases were positive for Plasmodium vivax by microscopy. Correspondingly, the OptiMal test identified malaria infection in 45 cases (69.2%) of microscopy positive cases. Of these, two cases were misinterpreted as Plasmodium falciparum, whereas ICT detected P. vivax infection in 29 (44.6%) patients. We would like to propose that rapid immuno capture assays are an easy method that can serve as a useful tool in addition to microscopy for the diagnosis of malaria, but sensitivity is not yet satisfactory for diagnosis of P. vivax in Korea.",

keywords = "ICT, Immunocapture assay, OptiMal, Plasmodium vivax, South Korea",

author = "Duck Cho and Kim, {Kwang Hee} and Park, {Seung Chul} and Kim, {Young Kee} and Lee, {Kap No} and Lim, {Chae Seung}",

note = "Funding Information: Acknowledgements We most gratefully acknowledge the financial support granted by the Medical Science Research Center of Korea University and the grant from the Ministry of Health and Welfare, Republic of Korea (Grant No HMP-99-M-04–0002).",

year = "2001",

doi = "10.1007/s004360000360",

language = "English",

volume = "87",

pages = "445--448",

journal = "Parasitology Research",

issn = "0932-0113",

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T1 - Evaluation of rapid immunocapture assays for diagnosis of Plasmodium vivax in Korea

AU - Cho, Duck

AU - Kim, Kwang Hee

AU - Park, Seung Chul

AU - Kim, Young Kee

AU - Lee, Kap No

AU - Lim, Chae Seung

N1 - Funding Information: Acknowledgements We most gratefully acknowledge the financial support granted by the Medical Science Research Center of Korea University and the grant from the Ministry of Health and Welfare, Republic of Korea (Grant No HMP-99-M-04–0002).

PY - 2001

Y1 - 2001

N2 - The rapid immunocapture assays, OptiMal and ICT, were evaluated from 87 individuals for the diagnosis of malaria infections directly from whole blood. A total of 87 individuals was examined for malaria parasites by microscopic examination of Giemsastained blood smears, and 65 cases were positive for Plasmodium vivax by microscopy. Correspondingly, the OptiMal test identified malaria infection in 45 cases (69.2%) of microscopy positive cases. Of these, two cases were misinterpreted as Plasmodium falciparum, whereas ICT detected P. vivax infection in 29 (44.6%) patients. We would like to propose that rapid immuno capture assays are an easy method that can serve as a useful tool in addition to microscopy for the diagnosis of malaria, but sensitivity is not yet satisfactory for diagnosis of P. vivax in Korea.

AB - The rapid immunocapture assays, OptiMal and ICT, were evaluated from 87 individuals for the diagnosis of malaria infections directly from whole blood. A total of 87 individuals was examined for malaria parasites by microscopic examination of Giemsastained blood smears, and 65 cases were positive for Plasmodium vivax by microscopy. Correspondingly, the OptiMal test identified malaria infection in 45 cases (69.2%) of microscopy positive cases. Of these, two cases were misinterpreted as Plasmodium falciparum, whereas ICT detected P. vivax infection in 29 (44.6%) patients. We would like to propose that rapid immuno capture assays are an easy method that can serve as a useful tool in addition to microscopy for the diagnosis of malaria, but sensitivity is not yet satisfactory for diagnosis of P. vivax in Korea.

KW - ICT

KW - Immunocapture assay

KW - OptiMal

KW - Plasmodium vivax

KW - South Korea

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U2 - 10.1007/s004360000360

DO - 10.1007/s004360000360

M3 - Article

C2 - 11411942

AN - SCOPUS:0035031825

SN - 0932-0113

VL - 87

SP - 445

EP - 448

JO - Parasitology Research

JF - Parasitology Research

IS - 6

ER -

Evaluation of rapid immunocapture assays for diagnosis of Plasmodium vivax in Korea

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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