The rapid immunocapture assays, OptiMal and ICT, were evaluated from 87 individuals for the diagnosis of malaria infections directly from whole blood. A total of 87 individuals was examined for malaria parasites by microscopic examination of Giemsastained blood smears, and 65 cases were positive for Plasmodium vivax by microscopy. Correspondingly, the OptiMal test identified malaria infection in 45 cases (69.2%) of microscopy positive cases. Of these, two cases were misinterpreted as Plasmodium falciparum, whereas ICT detected P. vivax infection in 29 (44.6%) patients. We would like to propose that rapid immuno capture assays are an easy method that can serve as a useful tool in addition to microscopy for the diagnosis of malaria, but sensitivity is not yet satisfactory for diagnosis of P. vivax in Korea.
Bibliographical noteFunding Information:
Acknowledgements We most gratefully acknowledge the financial support granted by the Medical Science Research Center of Korea University and the grant from the Ministry of Health and Welfare, Republic of Korea (Grant No HMP-99-M-04–0002).
- Immunocapture assay
- Plasmodium vivax
- South Korea
ASJC Scopus subject areas
- Insect Science
- Infectious Diseases