Exploiting the natural metabolic diversity of Streptomyces venezuelae to generate unusual reduced macrolides

Je Won Park; Hong Se Oh; Won Seok Jung; Sung Ryeol Park; Ah Reum Han; Yeon Hee Ban; Eun Ji Kim; Han Young Kang; Yeo Joon Yoon

doi:10.1039/b814603a

Exploiting the natural metabolic diversity of Streptomyces venezuelae to generate unusual reduced macrolides

Je Won Park, Hong Se Oh, Won Seok Jung, Sung Ryeol Park, Ah Reum Han, Yeon Hee Ban, Eun Ji Kim, Han Young Kang, Yeo Joon Yoon

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

An unusual set of reduced macrolide antibiotics was discovered by combination of organic synthesis and a biosynthetic approach using the unique metabolic diversity of Streptomyces venezuelae; two unnatural 16-membered ring macrolides are also created by employing this bio-catalyst.

Original language	English
Pages (from-to)	5782-5784
Number of pages	3
Journal	Chemical Communications
Issue number	44
DOIs	https://doi.org/10.1039/b814603a
Publication status	Published - 2008
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/b814603a

Cite this

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title = "Exploiting the natural metabolic diversity of Streptomyces venezuelae to generate unusual reduced macrolides",

abstract = "An unusual set of reduced macrolide antibiotics was discovered by combination of organic synthesis and a biosynthetic approach using the unique metabolic diversity of Streptomyces venezuelae; two unnatural 16-membered ring macrolides are also created by employing this bio-catalyst.",

author = "Park, {Je Won} and Oh, {Hong Se} and Jung, {Won Seok} and Park, {Sung Ryeol} and Han, {Ah Reum} and Ban, {Yeon Hee} and Kim, {Eun Ji} and Kang, {Han Young} and Yoon, {Yeo Joon}",

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AU - Park, Je Won

AU - Oh, Hong Se

AU - Jung, Won Seok

AU - Park, Sung Ryeol

AU - Han, Ah Reum

AU - Ban, Yeon Hee

AU - Kim, Eun Ji

AU - Kang, Han Young

AU - Yoon, Yeo Joon

PY - 2008

Y1 - 2008

N2 - An unusual set of reduced macrolide antibiotics was discovered by combination of organic synthesis and a biosynthetic approach using the unique metabolic diversity of Streptomyces venezuelae; two unnatural 16-membered ring macrolides are also created by employing this bio-catalyst.

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JO - Chemical Communications

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Exploiting the natural metabolic diversity of Streptomyces venezuelae to generate unusual reduced macrolides

Abstract

ASJC Scopus subject areas

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