Exposure Monitoring and Health Risk Assessment of 1-Bromopropane as a Cleaning Solvent in the Workplace

Hyung Il Moon; Saemi Shin; Sang Hoon Byeon

doi:10.1080/10807039.2014.926203

Exposure Monitoring and Health Risk Assessment of 1-Bromopropane as a Cleaning Solvent in the Workplace

Hyung Il Moon
, Saemi Shin
, Sang Hoon Byeon^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

ABSTRACT: This study was conducted to estimate the health risk to workers exposed to 1-bromopropane (1-BP) used as a cleaning solvent in their workplaces. Fifty samples from 10 workplaces that use 1-BP as a cleaning solvent were obtained to assess 1-BP concentrations. An exposure assessment revealed central tendency exposure (CTE) and reasonable maximum exposure (RME) levels of 82.1 and 214.8 mg/m³, respectively. For risk characterization, the 1-BP exposure concentrations for reproductive and developmental toxicities were calculated as 2.8 and 8.5 mg/m³, respectively, and compared with the reference concentrations in the workplace. The CTE and RME hazard quotients (HQ) were, respectively, 29.4 and 77.0 for reproductive toxicity and 9.6 and 25.2 for developmental toxicity. The results of our 1-BP risk assessment indicated that the CTE-HQs for both categories were higher than the acceptable risk value of 1, indicating that 1-BP may be considered as harmful to workers.

Original language	English
Pages (from-to)	744-752
Number of pages	9
Journal	Human and Ecological Risk Assessment
Volume	21
Issue number	3
DOIs	https://doi.org/10.1080/10807039.2014.926203
Publication status	Published - 2015 Apr 3

Bibliographical note

Publisher Copyright:
© 2015, Copyright © Taylor & Francis Group, LLC.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

1-bromopropane
Monte Carlo simulation
point of departure
reference concentration
risk assessment

ASJC Scopus subject areas

Ecological Modelling
Pollution
Health, Toxicology and Mutagenesis

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10.1080/10807039.2014.926203

Cite this

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title = "Exposure Monitoring and Health Risk Assessment of 1-Bromopropane as a Cleaning Solvent in the Workplace",

abstract = "ABSTRACT: This study was conducted to estimate the health risk to workers exposed to 1-bromopropane (1-BP) used as a cleaning solvent in their workplaces. Fifty samples from 10 workplaces that use 1-BP as a cleaning solvent were obtained to assess 1-BP concentrations. An exposure assessment revealed central tendency exposure (CTE) and reasonable maximum exposure (RME) levels of 82.1 and 214.8 mg/m3, respectively. For risk characterization, the 1-BP exposure concentrations for reproductive and developmental toxicities were calculated as 2.8 and 8.5 mg/m3, respectively, and compared with the reference concentrations in the workplace. The CTE and RME hazard quotients (HQ) were, respectively, 29.4 and 77.0 for reproductive toxicity and 9.6 and 25.2 for developmental toxicity. The results of our 1-BP risk assessment indicated that the CTE-HQs for both categories were higher than the acceptable risk value of 1, indicating that 1-BP may be considered as harmful to workers.",

keywords = "1-bromopropane, Monte Carlo simulation, point of departure, reference concentration, risk assessment",

author = "Moon, \{Hyung Il\} and Saemi Shin and Byeon, \{Sang Hoon\}",

note = "Publisher Copyright: {\textcopyright} 2015, Copyright {\textcopyright} Taylor \& Francis Group, LLC.",

year = "2015",

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day = "3",

doi = "10.1080/10807039.2014.926203",

language = "English",

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T1 - Exposure Monitoring and Health Risk Assessment of 1-Bromopropane as a Cleaning Solvent in the Workplace

AU - Moon, Hyung Il

AU - Shin, Saemi

AU - Byeon, Sang Hoon

PY - 2015/4/3

Y1 - 2015/4/3

N2 - ABSTRACT: This study was conducted to estimate the health risk to workers exposed to 1-bromopropane (1-BP) used as a cleaning solvent in their workplaces. Fifty samples from 10 workplaces that use 1-BP as a cleaning solvent were obtained to assess 1-BP concentrations. An exposure assessment revealed central tendency exposure (CTE) and reasonable maximum exposure (RME) levels of 82.1 and 214.8 mg/m3, respectively. For risk characterization, the 1-BP exposure concentrations for reproductive and developmental toxicities were calculated as 2.8 and 8.5 mg/m3, respectively, and compared with the reference concentrations in the workplace. The CTE and RME hazard quotients (HQ) were, respectively, 29.4 and 77.0 for reproductive toxicity and 9.6 and 25.2 for developmental toxicity. The results of our 1-BP risk assessment indicated that the CTE-HQs for both categories were higher than the acceptable risk value of 1, indicating that 1-BP may be considered as harmful to workers.

AB - ABSTRACT: This study was conducted to estimate the health risk to workers exposed to 1-bromopropane (1-BP) used as a cleaning solvent in their workplaces. Fifty samples from 10 workplaces that use 1-BP as a cleaning solvent were obtained to assess 1-BP concentrations. An exposure assessment revealed central tendency exposure (CTE) and reasonable maximum exposure (RME) levels of 82.1 and 214.8 mg/m3, respectively. For risk characterization, the 1-BP exposure concentrations for reproductive and developmental toxicities were calculated as 2.8 and 8.5 mg/m3, respectively, and compared with the reference concentrations in the workplace. The CTE and RME hazard quotients (HQ) were, respectively, 29.4 and 77.0 for reproductive toxicity and 9.6 and 25.2 for developmental toxicity. The results of our 1-BP risk assessment indicated that the CTE-HQs for both categories were higher than the acceptable risk value of 1, indicating that 1-BP may be considered as harmful to workers.

KW - 1-bromopropane

KW - Monte Carlo simulation

KW - point of departure

KW - reference concentration

KW - risk assessment

UR - https://www.scopus.com/pages/publications/84911007497

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DO - 10.1080/10807039.2014.926203

M3 - Article

AN - SCOPUS:84911007497

SN - 1080-7039

VL - 21

SP - 744

EP - 752

JO - Human and Ecological Risk Assessment

JF - Human and Ecological Risk Assessment

IS - 3

ER -

Exposure Monitoring and Health Risk Assessment of 1-Bromopropane as a Cleaning Solvent in the Workplace

Abstract

Bibliographical note

UN SDGs

Keywords

ASJC Scopus subject areas

Access to Document

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