Extracellular RNA: Emerging roles in cancer cell communication and biomarkers

Seokho Kim; Ok Hee Jeon; Young Jun Jeon

doi:10.1016/j.canlet.2020.09.002

Extracellular RNA: Emerging roles in cancer cell communication and biomarkers

Seokho Kim, Ok Hee Jeon, Young Jun Jeon

Research output: Contribution to journal › Review article › peer-review

15 Citations (Scopus)

Abstract

Extracellular RNAs (exRNAs) are a type of RNA molecules that present in various biological fluids. exRNAs are heterogenous populations including small (e.g., miRNA) and long non-coding RNAs and coding RNAs (e.g., mRNA). They can exist in a free form or associate with carriers range from lipo- and ribo-proteins to extracellular vesicles such as exosomes in the extracellular fluids. exRNAs participate in cell-to-cell communication to regulate a broad array of physiological and pathological processes. exRNAs have been widely studied as a biomarker for cancer and other diseases. In this review, we will discuss the sorts of exRNAs with potential carriers as well as their roles in cancer.

Original language	English
Pages (from-to)	33-40
Number of pages	8
Journal	Cancer letters
Volume	495
DOIs	https://doi.org/10.1016/j.canlet.2020.09.002
Publication status	Published - 2020 Dec 28

Bibliographical note

Publisher Copyright:
© 2020 Elsevier B.V.

ASJC Scopus subject areas

Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.canlet.2020.09.002

Cite this

@article{29f26ee0ef3348d99008633516b06044,

title = "Extracellular RNA: Emerging roles in cancer cell communication and biomarkers",

abstract = "Extracellular RNAs (exRNAs) are a type of RNA molecules that present in various biological fluids. exRNAs are heterogenous populations including small (e.g., miRNA) and long non-coding RNAs and coding RNAs (e.g., mRNA). They can exist in a free form or associate with carriers range from lipo- and ribo-proteins to extracellular vesicles such as exosomes in the extracellular fluids. exRNAs participate in cell-to-cell communication to regulate a broad array of physiological and pathological processes. exRNAs have been widely studied as a biomarker for cancer and other diseases. In this review, we will discuss the sorts of exRNAs with potential carriers as well as their roles in cancer.",

author = "Seokho Kim and Jeon, {Ok Hee} and Jeon, {Young Jun}",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier B.V.",

year = "2020",

month = dec,

day = "28",

doi = "10.1016/j.canlet.2020.09.002",

language = "English",

volume = "495",

pages = "33--40",

journal = "Cancer letters",

issn = "0304-3835",

publisher = "Elsevier Ireland Ltd",

}

TY - JOUR

T1 - Extracellular RNA

T2 - Emerging roles in cancer cell communication and biomarkers

AU - Kim, Seokho

AU - Jeon, Ok Hee

AU - Jeon, Young Jun

PY - 2020/12/28

Y1 - 2020/12/28

N2 - Extracellular RNAs (exRNAs) are a type of RNA molecules that present in various biological fluids. exRNAs are heterogenous populations including small (e.g., miRNA) and long non-coding RNAs and coding RNAs (e.g., mRNA). They can exist in a free form or associate with carriers range from lipo- and ribo-proteins to extracellular vesicles such as exosomes in the extracellular fluids. exRNAs participate in cell-to-cell communication to regulate a broad array of physiological and pathological processes. exRNAs have been widely studied as a biomarker for cancer and other diseases. In this review, we will discuss the sorts of exRNAs with potential carriers as well as their roles in cancer.

AB - Extracellular RNAs (exRNAs) are a type of RNA molecules that present in various biological fluids. exRNAs are heterogenous populations including small (e.g., miRNA) and long non-coding RNAs and coding RNAs (e.g., mRNA). They can exist in a free form or associate with carriers range from lipo- and ribo-proteins to extracellular vesicles such as exosomes in the extracellular fluids. exRNAs participate in cell-to-cell communication to regulate a broad array of physiological and pathological processes. exRNAs have been widely studied as a biomarker for cancer and other diseases. In this review, we will discuss the sorts of exRNAs with potential carriers as well as their roles in cancer.

UR - http://www.scopus.com/inward/record.url?scp=85091242145&partnerID=8YFLogxK

U2 - 10.1016/j.canlet.2020.09.002

DO - 10.1016/j.canlet.2020.09.002

M3 - Review article

C2 - 32916182

AN - SCOPUS:85091242145

SN - 0304-3835

VL - 495

SP - 33

EP - 40

JO - Cancer letters

JF - Cancer letters

ER -

Extracellular RNA: Emerging roles in cancer cell communication and biomarkers

Abstract

Bibliographical note

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this