Fabrication of poly(ε-caprolactone)/hydroxyapatite scaffold using rapid direct deposition

Young Hag Koh; In Kook Jun; Hyoun Ee Kim

doi:10.1016/j.matlet.2005.10.103

Fabrication of poly(ε-caprolactone)/hydroxyapatite scaffold using rapid direct deposition

Young Hag Koh, In Kook Jun, Hyoun Ee Kim

Research output: Contribution to journal › Article › peer-review

39 Citations (Scopus)

Abstract

Macrochanneled poly(ε-caprolactone) (PCL)/hydroxyapatite (HA) scaffolds were fabricated using the rapid direct deposition process, in which a warm PCL-HA/acetone slurry was deposited through an 520-μm orifice in an ethanol coagulation reservoir, producing a continuous rigid filament via solvent extraction. This method allowed the macrochanneled PCL/HA scaffolds to have a controlled structure, which was constructed using a ∼330-μm filament, in which the HA particles were well dispersed in the PCL matrix. The bonding between the deposited filaments was further enhanced by post heat-treatment at 60 °C for 30 min. The fabricated scaffold showed linear elasticity followed by densification without catastrophic failure, owing to the rubbery characteristic of the PCL polymer.

Original language	English
Pages (from-to)	1184-1187
Number of pages	4
Journal	Materials Letters
Volume	60
Issue number	9-10
DOIs	https://doi.org/10.1016/j.matlet.2005.10.103
Publication status	Published - 2006 May
Externally published	Yes

Bibliographical note

Funding Information:
This work was supported by a grant from the Korea Health 21 R&D Project, the ministry of Health and Welfare, Republic of Korea (02-PJ3-PG6EV11-0002).

Keywords

Hydroxyapatite
Poly(ε-caprolactone)
Rapid prototyping
Scaffold

ASJC Scopus subject areas

Materials Science(all)
Condensed Matter Physics
Mechanics of Materials
Mechanical Engineering

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10.1016/j.matlet.2005.10.103

Cite this

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title = "Fabrication of poly(ε-caprolactone)/hydroxyapatite scaffold using rapid direct deposition",

abstract = "Macrochanneled poly(ε-caprolactone) (PCL)/hydroxyapatite (HA) scaffolds were fabricated using the rapid direct deposition process, in which a warm PCL-HA/acetone slurry was deposited through an 520-μm orifice in an ethanol coagulation reservoir, producing a continuous rigid filament via solvent extraction. This method allowed the macrochanneled PCL/HA scaffolds to have a controlled structure, which was constructed using a ∼330-μm filament, in which the HA particles were well dispersed in the PCL matrix. The bonding between the deposited filaments was further enhanced by post heat-treatment at 60 °C for 30 min. The fabricated scaffold showed linear elasticity followed by densification without catastrophic failure, owing to the rubbery characteristic of the PCL polymer.",

keywords = "Hydroxyapatite, Poly(ε-caprolactone), Rapid prototyping, Scaffold",

author = "Koh, {Young Hag} and Jun, {In Kook} and Kim, {Hyoun Ee}",

note = "Funding Information: This work was supported by a grant from the Korea Health 21 R&D Project, the ministry of Health and Welfare, Republic of Korea (02-PJ3-PG6EV11-0002).",

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AU - Koh, Young Hag

AU - Jun, In Kook

AU - Kim, Hyoun Ee

N1 - Funding Information: This work was supported by a grant from the Korea Health 21 R&D Project, the ministry of Health and Welfare, Republic of Korea (02-PJ3-PG6EV11-0002).

PY - 2006/5

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N2 - Macrochanneled poly(ε-caprolactone) (PCL)/hydroxyapatite (HA) scaffolds were fabricated using the rapid direct deposition process, in which a warm PCL-HA/acetone slurry was deposited through an 520-μm orifice in an ethanol coagulation reservoir, producing a continuous rigid filament via solvent extraction. This method allowed the macrochanneled PCL/HA scaffolds to have a controlled structure, which was constructed using a ∼330-μm filament, in which the HA particles were well dispersed in the PCL matrix. The bonding between the deposited filaments was further enhanced by post heat-treatment at 60 °C for 30 min. The fabricated scaffold showed linear elasticity followed by densification without catastrophic failure, owing to the rubbery characteristic of the PCL polymer.

AB - Macrochanneled poly(ε-caprolactone) (PCL)/hydroxyapatite (HA) scaffolds were fabricated using the rapid direct deposition process, in which a warm PCL-HA/acetone slurry was deposited through an 520-μm orifice in an ethanol coagulation reservoir, producing a continuous rigid filament via solvent extraction. This method allowed the macrochanneled PCL/HA scaffolds to have a controlled structure, which was constructed using a ∼330-μm filament, in which the HA particles were well dispersed in the PCL matrix. The bonding between the deposited filaments was further enhanced by post heat-treatment at 60 °C for 30 min. The fabricated scaffold showed linear elasticity followed by densification without catastrophic failure, owing to the rubbery characteristic of the PCL polymer.

KW - Hydroxyapatite

KW - Poly(ε-caprolactone)

KW - Rapid prototyping

KW - Scaffold

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JO - Materials Letters

JF - Materials Letters

IS - 9-10

ER -

Fabrication of poly(ε-caprolactone)/hydroxyapatite scaffold using rapid direct deposition

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

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