Facile synthesis of benzo[4,5]furo[3,2-c]pyridines via palladium-catalyzed intramolecular Heck reaction

Woo Sub Yoon; Su Jung Lee; Seung Kyu Kang; Deok Chan Ha; Jae Du Ha

doi:10.1016/j.tetlet.2009.05.063

Facile synthesis of benzo[4,5]furo[3,2-c]pyridines via palladium-catalyzed intramolecular Heck reaction

Woo Sub Yoon, Su Jung Lee, Seung Kyu Kang, Deok Chan Ha, Jae Du Ha

College of Science

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

The heating of 4-chloropyridine with 2-bromophenol in either neat or DME as solvent gives rise to 2-bromophenoxy pyridines, which were treated with Pd(OAc)₂ and various ligands to afford functionalized benzo[4,5]furo[3,2-c]pyridines.

Original language	English
Pages (from-to)	4492-4494
Number of pages	3
Journal	Tetrahedron Letters
Volume	50
Issue number	31
DOIs	https://doi.org/10.1016/j.tetlet.2009.05.063
Publication status	Published - 2009 Aug 5

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tetlet.2009.05.063

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title = "Facile synthesis of benzo[4,5]furo[3,2-c]pyridines via palladium-catalyzed intramolecular Heck reaction",

abstract = "The heating of 4-chloropyridine with 2-bromophenol in either neat or DME as solvent gives rise to 2-bromophenoxy pyridines, which were treated with Pd(OAc)2 and various ligands to afford functionalized benzo[4,5]furo[3,2-c]pyridines.",

author = "Yoon, {Woo Sub} and Lee, {Su Jung} and Kang, {Seung Kyu} and Ha, {Deok Chan} and Ha, {Jae Du}",

note = "Funding Information: We are grateful to the Korea Research Institute of Chemical Technology for financial support. ",

year = "2009",

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doi = "10.1016/j.tetlet.2009.05.063",

language = "English",

volume = "50",

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journal = "Tetrahedron Letters",

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T1 - Facile synthesis of benzo[4,5]furo[3,2-c]pyridines via palladium-catalyzed intramolecular Heck reaction

AU - Yoon, Woo Sub

AU - Lee, Su Jung

AU - Kang, Seung Kyu

AU - Ha, Deok Chan

AU - Ha, Jae Du

N1 - Funding Information: We are grateful to the Korea Research Institute of Chemical Technology for financial support.

PY - 2009/8/5

Y1 - 2009/8/5

N2 - The heating of 4-chloropyridine with 2-bromophenol in either neat or DME as solvent gives rise to 2-bromophenoxy pyridines, which were treated with Pd(OAc)2 and various ligands to afford functionalized benzo[4,5]furo[3,2-c]pyridines.

AB - The heating of 4-chloropyridine with 2-bromophenol in either neat or DME as solvent gives rise to 2-bromophenoxy pyridines, which were treated with Pd(OAc)2 and various ligands to afford functionalized benzo[4,5]furo[3,2-c]pyridines.

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U2 - 10.1016/j.tetlet.2009.05.063

DO - 10.1016/j.tetlet.2009.05.063

M3 - Article

AN - SCOPUS:66949162312

SN - 0040-4039

VL - 50

SP - 4492

EP - 4494

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 31

ER -

Facile synthesis of benzo[4,5]furo[3,2-c]pyridines via palladium-catalyzed intramolecular Heck reaction

Abstract

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