Facile synthesis of benzo[4,5]furo[3,2-c]pyridines via palladium-catalyzed intramolecular Heck reaction

Woo Sub Yoon; Su Jung Lee; Seung Kyu Kang; Deok Chan Ha; Jae Du Ha

doi:10.1016/j.tetlet.2009.05.063

Facile synthesis of benzo[4,5]furo[3,2-c]pyridines via palladium-catalyzed intramolecular Heck reaction

Woo Sub Yoon, Su Jung Lee, Seung Kyu Kang, Deok Chan Ha, Jae Du Ha

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

The heating of 4-chloropyridine with 2-bromophenol in either neat or DME as solvent gives rise to 2-bromophenoxy pyridines, which were treated with Pd(OAc)₂ and various ligands to afford functionalized benzo[4,5]furo[3,2-c]pyridines.

Original language	English
Pages (from-to)	4492-4494
Number of pages	3
Journal	Tetrahedron Letters
Volume	50
Issue number	31
DOIs	https://doi.org/10.1016/j.tetlet.2009.05.063
Publication status	Published - 2009 Aug 5

Bibliographical note

Funding Information:
We are grateful to the Korea Research Institute of Chemical Technology for financial support.

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

Access to Document

10.1016/j.tetlet.2009.05.063

Cite this

@article{eacc31438c0e463486e1df35522902d1,

title = "Facile synthesis of benzo[4,5]furo[3,2-c]pyridines via palladium-catalyzed intramolecular Heck reaction",

abstract = "The heating of 4-chloropyridine with 2-bromophenol in either neat or DME as solvent gives rise to 2-bromophenoxy pyridines, which were treated with Pd(OAc)2 and various ligands to afford functionalized benzo[4,5]furo[3,2-c]pyridines.",

author = "Yoon, {Woo Sub} and Lee, {Su Jung} and Kang, {Seung Kyu} and Ha, {Deok Chan} and Ha, {Jae Du}",

note = "Funding Information: We are grateful to the Korea Research Institute of Chemical Technology for financial support. ",

year = "2009",

month = aug,

day = "5",

doi = "10.1016/j.tetlet.2009.05.063",

language = "English",

volume = "50",

pages = "4492--4494",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Limited",

number = "31",

}

TY - JOUR

T1 - Facile synthesis of benzo[4,5]furo[3,2-c]pyridines via palladium-catalyzed intramolecular Heck reaction

AU - Yoon, Woo Sub

AU - Lee, Su Jung

AU - Kang, Seung Kyu

AU - Ha, Deok Chan

AU - Ha, Jae Du

N1 - Funding Information: We are grateful to the Korea Research Institute of Chemical Technology for financial support.

PY - 2009/8/5

Y1 - 2009/8/5

N2 - The heating of 4-chloropyridine with 2-bromophenol in either neat or DME as solvent gives rise to 2-bromophenoxy pyridines, which were treated with Pd(OAc)2 and various ligands to afford functionalized benzo[4,5]furo[3,2-c]pyridines.

AB - The heating of 4-chloropyridine with 2-bromophenol in either neat or DME as solvent gives rise to 2-bromophenoxy pyridines, which were treated with Pd(OAc)2 and various ligands to afford functionalized benzo[4,5]furo[3,2-c]pyridines.

UR - http://www.scopus.com/inward/record.url?scp=66949162312&partnerID=8YFLogxK

U2 - 10.1016/j.tetlet.2009.05.063

DO - 10.1016/j.tetlet.2009.05.063

M3 - Article

AN - SCOPUS:66949162312

SN - 0040-4039

VL - 50

SP - 4492

EP - 4494

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 31

ER -

Facile synthesis of benzo[4,5]furo[3,2-c]pyridines via palladium-catalyzed intramolecular Heck reaction

Abstract

Bibliographical note

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this