Farnesylation-defective rheb increases axonal length independently of mTORC1 activity in embryonic primary neurons

Keyphrases

• Mammalian Target of Rapamycin (mTOR) 100%
• Primary Neurons 100%
• Axonal Length 100%
• Farnesylation 100%
• Rheb 100%
• 4E-BP1 25%
• Membrane Compartments 25%
• Axonal Elongation 25%
• Lysosomal Membrane 25%
• Biological Processes 12%
• Transfected Cells 12%
• Phosphorylation 12%
• Rapamycin 12%
• Mutant Forms 12%
• Cell Signaling 12%
• Promotion Effect 12%
• Cysteine Residues 12%
• Downstream Targets 12%
• Neocortex 12%
• Independent Pathway 12%
• Axon 12%
• Axonal Growth 12%
• Small GTP-binding Proteins 12%
• Cultured Hippocampal Neurons 12%
• Control Vector 12%
• Transfectant 12%
• Embryonic Neurons 12%
• Promoting Effect 12%
• In Utero Electroporation 12%
• C180 12%
• Axon Elongation 12%

Biochemistry, Genetics and Molecular Biology

• Mammalian Target of Rapamycin Complex 1 100%
• Wild Type 33%
• Mammalian Target of Rapamycin 33%
• Axon 33%
• Signal Transduction 16%
• Biological Phenomena and Functions Concerning the Entire Organism 16%
• Complex Formation 16%
• Small GTPase 16%
• Independent Pathway 16%
• Electroporation 16%
• Cysteine 16%

Neuroscience

• Mammalian Target of Rapamycin Complex 1 100%
• Axon 33%
• Cell Signaling 16%
• Cysteine 16%
• GTPase 16%
• Complex Formation 16%
• Electroporation 16%
• Sirolimus 16%